Amplification of oxidative stress is present since the early stages of chronic kidney disease
(CKD), holding a key position in the pathogenesis of renal failure. Induction of renal pro …

Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

Background Hyperglycaemia associated with myocardial oxidative stress and fibrosis is the
main cause of diabetic cardiomyopathy. Empagliflozin, a sodium-glucose cotransporter 2 …

Oxidative stress (OS) is the result of prooxidant molecules overwhelming the antioxidant
defense mechanisms. Hemodialysis (HD) constitutes a state of elevated inflammation and …

Several studies have suggested that long intergenic noncoding RNAs are involved in the
progression of diabetic nephropathy (DN). However, the exact role and regulatory …

Renal failure is a major health problem that is increasing worldwide. To improve clinical
outcomes, we need to understand the basic mechanisms of kidney disease. Aging is a risk …

Objective Evidence suggests that both serum uric acid (SUA) and high-density lipoprotein
cholesterol (HDL-C) are risk factors for chronic kidney disease (CKD). The SUA-to-HDL-C …

The disruption of balance between production of reactive oxygen species and antioxidant
systems in favor of the oxidants is termed oxidative stress (OS). To counteract the damaging …

Background: In end-stage renal disease (ESRD), gut-derived uremic toxins play a crucial
role in the systemic inflammation and oxidative stress promoting the excess morbidity and …

Arterial calcification is highly prevalent in chronic kidney disease (CKD) patients and is
associated with cardiovascular (CV) morbidity and mortality. Patients at early CKD stages …