Horizontal transfer of genomic islands (GEIs), that is, chromosomal regions encoding
functions that can be advantageous for the host, plays a key role in bacterial evolution, but …

Antibiotic resistance is a major concern for society because it threatens the effective
prevention of infectious diseases. While some bacterial strains display intrinsic resistance …

Bacteriophages insert their DNA into host chromosomes either through transposition (as in
phage Mu) or through site-specific recombination (as in phage X). Whereas Mu can insert …

Abstract A 2· 1 kb (1 kb= 10 3 base-pairs) segment of DNA from the streptomycete
bacteriophage φC31 was found to be sufficient to direct site-specific integration of plasmid …

A virulence‐associated region in the genome of Dichelobacter nodosus has been shown to
contain an integrase gene which is highly related to the integrases of Shigella flexneri …

Plasmids and bacteriophage represent the classical vectors for gene transfer within the
horizontal gene pool. However, the more recent discovery of an increasing array of other …

Similarity between the DNA substrates and products of integrase-mediated site-specific
recombination reactions results in a single recombinase enzyme being able to catalyze both …

Eriodictyol is a hydroxylated flavonoid displaying multiple pharmaceutical activities, such as
antitumoral, antiviral or neuroprotective. However, its industrial production is limited to …

The DNA sequence of the Sulfolobus shibatae virus SSV1 is the first complete sequence of
an archaebacterial virus genome. The viral DNA is a closed double-stranded DNA circle of …

We have developed vectors which allowed integration of cloned DNA at a single site in the
chromosome of Streptomyces lividans 66. These vectors made use of (1) an Escherichia coli …