Free radicals have acquired growing importance in the fields of biology and medicine. They
are produced during many different endogenous and exogenous processes. Mitochondria …

Initially adopted as a mucolytic about 60 years ago, the cysteine prodrug N-acetylcysteine
(NAC) is the standard of care to treat paracetamol intoxication, and is included on the World …

Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …

As the first discovered gaseous signaling molecule, nitric oxide (NO) affects a number of
cellular processes, including those involving vascular cells. This brief review summarizes …

Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

The transsulfuration pathway is a metabolic pathway where transfer of sulfur from
homocysteine to cysteine occurs. The pathway leads to the generation of several sulfur …