This paper briefly reviews the physiological components of the microcirculation, focusing on
its function in homeostasis and its central function in the realization of oxygen transport to …

Sepsis is a multifactorial syndrome primarily determined by the host response to an invading
pathogen. It is common, with over 48 million cases worldwide in 2017, and often lethal. The …

Purpose Shock is a life-threatening condition characterized by substantial alterations in the
microcirculation. This study tests the hypothesis that considering sublingual microcirculatory …

Background Intravenous fluids, an essential component of sepsis resuscitation, may
paradoxically worsen outcomes by exacerbating endothelial injury. Preclinical models …

Background The endothelial glycocalyx (eGC) covers the luminal surface of the vascular
endothelium and plays an important protective role in systemic inflammatory states and …

Background The availability of handheld, noninvasive sublingual video-microscopes allows
for visualization of the microcirculation in critically ill patients. Recent studies demonstrate …

OBJECTIVES: In this study, we hypothesized that coronavirus disease 2019 patients exhibit
sublingual microcirculatory alterations caused by inflammation, coagulopathy, and …

The burden of pandemic COVID-19 is growing worldwide, as the continuous increases of
contagion. Only 10–15% of the entire infected population has the necessity of intensive care …

Objectives: This observational study was conducted to investigate capillary refill time (CRT)
during the early phase of ICU admission in relationship with microvascular flow alteration …

Objectives: Reliable automated handheld vital microscopy image sequence analysis and
the identification of disease states and effects of therapy are prerequisites for the routine use …