Intranasal delivery of biologics to the central nervous system
JJ Lochhead, RG Thorne - Advanced drug delivery reviews, 2012 - Elsevier
Treatment of central nervous system (CNS) diseases is very difficult due to the blood–brain
barrier's (BBB) ability to severely restrict entry of all but small, non-polar compounds …
barrier's (BBB) ability to severely restrict entry of all but small, non-polar compounds …
Sustentacular cell enwrapment of olfactory receptor neuronal dendrites: an update
F Liang - Genes, 2020 - mdpi.com
The pseudostratified olfactory epithelium (OE) may histologically appear relatively simple,
but the cytological relations among its cell types, especially those between olfactory receptor …
but the cytological relations among its cell types, especially those between olfactory receptor …
COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
associated with acute and postacute cognitive and neuropsychiatric symptoms including …
associated with acute and postacute cognitive and neuropsychiatric symptoms including …
[HTML][HTML] COVID-19 induces neuroinflammation and loss of hippocampal neurogenesis
Abstract Infection with the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is associated with onset of neurological and psychiatric symptoms during and after the …
2) is associated with onset of neurological and psychiatric symptoms during and after the …
[HTML][HTML] SARS-CoV-2 infection of sustentacular cells disrupts olfactory signaling pathways
Loss of olfactory function has been commonly reported in SARS-CoV-2 infections. Recovery
from anosmia is not well understood. Previous studies showed that sustentacular cells, and …
from anosmia is not well understood. Previous studies showed that sustentacular cells, and …
COVID-19 anosmia: high prevalence, plural neuropathogenic mechanisms, and scarce neurotropism of SARS-CoV-2?
F Liang, DY Wang - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative pathogen
of coronavirus disease 2019 (COVID-19). It is known as a respiratory virus, but SARS-CoV-2 …
of coronavirus disease 2019 (COVID-19). It is known as a respiratory virus, but SARS-CoV-2 …
[图书][B] Neuroglia: function and pathology
A Verkhratsky, A Butt - 2023 - books.google.com
Diverse specialised neuroglial cells guarantee the development, preservation, and health of
the central nervous system, the peripheral nervous system, the enteric nervous system, and …
the central nervous system, the peripheral nervous system, the enteric nervous system, and …
The cellular basis of loss of smell in 2019-nCoV-infected individuals
A prominent clinical symptom of 2019-novel coronavirus (nCoV) infection is
hyposmia/anosmia (decrease or loss of sense of smell), along with general symptoms such …
hyposmia/anosmia (decrease or loss of sense of smell), along with general symptoms such …
The immune mechanism of the nasal epithelium in COVID-19–related olfactory dysfunction
S Chen, S Wang - Frontiers in Immunology, 2023 - frontiersin.org
During the first waves of the coronavirus disease 2019 (COVID-19) pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, olfactory …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, olfactory …
[HTML][HTML] Receptors involved in COVID-19-related anosmia: An update on the pathophysiology and the mechanistic aspects
Olfactory perception is an important physiological function for human well-being and health.
Loss of olfaction, or anosmia, caused by viral infections such as severe acute respiratory …
Loss of olfaction, or anosmia, caused by viral infections such as severe acute respiratory …