Next-generation sequencing (NGS) technology has expanded in the last decades with
significant improvements in the reliability, sequencing chemistry, pipeline analyses, data …

The SLC4 family consists of 10 genes (SLC4A1–5; SLC4A7–11). All encode integral
membrane proteins with very similar hydropathy plots—consistent with 10–14 …

The mammalian Slc4 (Solute carrier 4) family of transporters is a functionally diverse group
of 10 multi-spanning membrane proteins that includes three Cl-HCO3 exchangers (AE1–3) …

Breast cancer is a major health problem in both developing and developed countries. It is
the most frequently diagnosed female malignant disease in Arab populations. The incidence …

Fibroblast growth factor receptor (FGFR) signaling is involved in multiple biological
processes, including cell proliferation, survival, differentiation, migration, and apoptosis …

Mitochondria, which are multi-functional, have been implicated in cancer initiation,
progression, and metastasis due to metabolic alterations in transformed cells. Mitochondria …

Purpose To review new evidence on the benefits and harms of risk assessment, genetic
counseling, and genetic testing for BRCA-related cancer in women for the US Preventive …

Simple Summary The human genome produces various types of RNA molecules. A
significant portion of these are long non-coding RNAs (lncRNAs) exceeding 200 nts without …

Abstract Background Na+, HCO3–-cotransporter NBCn1/Slc4a7 accelerates murine breast
carcinogenesis. Lack of specific pharmacological tools previously restricted therapeutic …

Impaired mitochondrial oxidative phosphorylation (OXPHOS) capacity, accompanied by
enhanced glycolysis, is a key metabolic feature of cancer cells, but its underlying …