The current status of mesenchymal stromal cells: controversies, unresolved issues and some promising solutions to improve their therapeutic efficacy

D García-Bernal, M García-Arranz… - Frontiers in Cell and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) currently constitute the most frequently used cell type in
advanced therapies with different purposes, most of which are related with inflammatory …

Improved therapeutics of modified mesenchymal stem cells: an update

DKW Ocansey, B Pei, Y Yan, H Qian, X Zhang… - Journal of translational …, 2020 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) have attracted intense interest due
to their powerful intrinsic properties of self-regeneration, immunomodulation and multi …

NGF-p75 signaling coordinates skeletal cell migration during bone repair

J Xu, Z Li, RJ Tower, S Negri, Y Wang, CA Meyers… - Science …, 2022 - science.org
Bone regeneration following injury is initiated by inflammatory signals and occurs in
association with infiltration by sensory nerve fibers. Together, these events are believed to …

[HTML][HTML] Translational insights into stem cell preconditioning: from molecular mechanisms to preclinical applications

K Moeinabadi-Bidgoli, A Babajani… - Biomedicine & …, 2021 - Elsevier
Cell-based therapy (CBT) is a revolutionary approach for curing a variety of degenerative
diseases. Stem cell-based regenerative medicine is a novel strategy for treating tissue …

Bioengineered cellular and cell membrane-derived vehicles for actively targeted drug delivery: so near and yet so far

MY Thanuja, C Anupama, SH Ranganath - Advanced drug delivery reviews, 2018 - Elsevier
Cellular carriers for drug delivery are attractive alternatives to synthetic nanoparticles owing
to their innate homing/targeting abilities. Here, we review molecular interactions involved in …

[HTML][HTML] Articular cartilage regeneration: the role of endogenous mesenchymal stem/progenitor cell recruitment and migration

S Zhang, B Hu, W Liu, P Wang, X Lv, S Chen… - Seminars in arthritis and …, 2020 - Elsevier
Background Trauma-or osteoarthritis-related cartilage damage resulted in functional decline
of joints and heavy burden of public health. Recently, the reparative role of mesenchymal …

Accelerated infected wound healing by topical application of encapsulated Rosemary essential oil into nanostructured lipid carriers

K Khezri, MR Farahpour… - … Cells, Nanomedicine, and …, 2019 - Taylor & Francis
The pathogenic bacteria delay wound healing due to their interaction in the wound area.
This study is aimed to evaluate the efficiency of topical rosemary essential oil (REO) loaded …

Recent progress in stem cell modification for cardiac regeneration

H Lemcke, N Voronina, G Steinhoff… - Stem Cells …, 2018 - Wiley Online Library
During the past decades, stem cell‐based therapy has acquired a promising role in
regenerative medicine. The application of novel cell therapeutics for the treatment of …

Bone marrow mesenchymal stem cells in rheumatoid arthritis, spondyloarthritis, and ankylosing spondylitis: problems rather than solutions?

JM Berthelot, B Le Goff, Y Maugars - Arthritis research & therapy, 2019 - Springer
Background Bone marrow mesenchymal stem cells (BM-MSCs) can dampen inflammation
in animal models of inflammatory rheumatisms and human osteoarthritis. They are expected …

Mesenchymal stem cells in the pathogenesis and therapy of autoimmune and autoinflammatory diseases

LN Zaripova, A Midgley, SE Christmas… - International Journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) modulate immune responses and maintain self-tolerance.
Their trophic activities and regenerative properties make them potential …