Decellularized matrices in regenerative medicine
Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …
promising tool used either alone or when combined with other biologics in the fields of tissue …
Review of collagen I hydrogels for bioengineered tissue microenvironments: characterization of mechanics, structure, and transport
EE Antoine, PP Vlachos… - Tissue Engineering Part B …, 2014 - liebertpub.com
Type I collagen hydrogels have been used successfully as three-dimensional substrates for
cell culture and have shown promise as scaffolds for engineered tissues and tumors. A …
cell culture and have shown promise as scaffolds for engineered tissues and tumors. A …
Photocrosslinkable gelatin hydrogel for epidermal tissue engineering
Natural hydrogels are promising scaffolds to engineer epidermis. Currently, natural
hydrogels used to support epidermal regeneration are mainly collagen‐or gelatin‐based …
hydrogels used to support epidermal regeneration are mainly collagen‐or gelatin‐based …
Self-generated gradients steer collective migration on viscoelastic collagen networks
Growing evidence suggests that the physical properties of the cellular microenvironment
influence cell migration. However, it is not currently understood how active physical …
influence cell migration. However, it is not currently understood how active physical …
Biomimetic nanoengineered scaffold for enhanced full-thickness cutaneous wound healing
N Zandi, B Dolatyar, R Lotfi, Y Shallageh… - Acta biomaterialia, 2021 - Elsevier
Wound healing is a complex process based on the coordinated signaling molecules and
dynamic interactions between the engineered scaffold and newly formed tissue. So far, most …
dynamic interactions between the engineered scaffold and newly formed tissue. So far, most …
Strain-induced alignment in collagen gels
Collagen is the most abundant extracellular-network-forming protein in animal biology and
is important in both natural and artificial tissues, where it serves as a material of great …
is important in both natural and artificial tissues, where it serves as a material of great …
Ultrarapid engineering of biomimetic materials and tissues: Fabrication of nano‐and microstructures by plastic compression
RA Brown, M Wiseman, CB Chuo… - Advanced functional …, 2005 - Wiley Online Library
Currently, the concept of engineered tissues depends on the ability of cultured cells to
fabricate new tissue around a scaffold. This is inherently slow and expensive and has had …
fabricate new tissue around a scaffold. This is inherently slow and expensive and has had …
6-deoxy-aminocellulose derivatives embedded soft gelatin methacryloyl (GelMA) hydrogels for improved wound healing applications: In vitro and in vivo studies
Hydrogels were prepared by mixing protein and carbohydrate-based biopolymers to
increase the mechanical properties and efficient cell adhesion and proliferation for wound …
increase the mechanical properties and efficient cell adhesion and proliferation for wound …
Mechanisms of plastic deformation in collagen networks induced by cellular forces
Contractile cells can reorganize fibrous extracellular matrices and form dense tracts of fibers
between neighboring cells. These tracts guide the development of tubular tissue structures …
between neighboring cells. These tracts guide the development of tubular tissue structures …
Mechanical strain stabilizes reconstituted collagen fibrils against enzymatic degradation by mammalian collagenase matrix metalloproteinase 8 (MMP-8)
Background Collagen, a triple-helical, self-organizing protein, is the predominant structural
protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin …
protein in mammals. It is found in bone, ligament, tendon, cartilage, intervertebral disc, skin …