Therapeutic strategies for COVID-19: progress and lessons learned

G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …

Probiotic improves symptomatic and viral clearance in Covid19 outpatients: a randomized, quadruple-blinded, placebo-controlled trial

P Gutiérrez-Castrellón, T Gandara-Martí… - Gut …, 2022 - Taylor & Francis
Intestinal bacteria may influence lung homeostasis via the gut-lung axis. We conducted a
single-center, quadruple-blinded, randomized trial in adult symptomatic Coronavirus …

Self-medication practices to prevent or manage COVID-19: A systematic review

A Quincho-Lopez, CA Benites-Ibarra… - PloS one, 2021 - journals.plos.org
Background Previous studies have assessed the prevalence and characteristics of self-
medication in COVID-19. However, no systematic review has summarized their findings …

Zinc and selenium supplementation in COVID-19 prevention and treatment: a systematic review of the experimental studies

E Balboni, F Zagnoli, T Filippini… - Journal of Trace …, 2022 - Elsevier
Background and aim The COVID-19 pandemic has severely affected the world's population
in the last two years. Along with non-pharmacological public health interventions, major …

Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2022 - Elsevier
Abstract oxidative stress is caused by an abundant generation of reactive oxygen species,
associated to a diminished capacity of the endogenous systems of the organism to …

Prophylaxis against covid-19: living systematic review and network meta-analysis

JJ Bartoszko, RAC Siemieniuk, E Kum, A Qasim… - Bmj, 2021 - bmj.com
Updates This is the second version (first update) of the living systematic review, replacing
the previous version (available as a data supplement). When citing this paper please …

Vitamin C in the Treatment of COVID-19

GP Milani, M Macchi, A Guz-Mark - Nutrients, 2021 - mdpi.com
Vitamin C is an essential nutrient that serves as antioxidant and plays a major role as co-
factor and modulator of various pathways of the immune system. Its therapeutic effect during …

Vitamin C reduces the severity of common colds: a meta-analysis

H Hemilä, E Chalker - BMC Public Health, 2023 - Springer
Background Randomized trials have shown that vitamin C shortens the duration of common
colds. Some trials reported greater effects on severe cold symptoms compared with mild …

Metabolic implications of oxidative stress and inflammatory process in SARS-CoV-2 pathogenesis: therapeutic potential of natural antioxidants

GE Forcados, A Muhammad, OO Oladipo… - Frontiers in Cellular …, 2021 - frontiersin.org
COVID-19 is a zoonotic disease with devastating economic and public health impacts
globally. Being a novel disease, current research is focused on a clearer understanding of …