Compositions and methods of improving specificity in genomic engineering using rna-guided endonucleases
E Josephs, D Kocak, P Marszalek… - US Patent …, 2022 - Google Patents
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
Crispr/cas-related methods and compositions for treating duchenne muscular dystrophy
DA Bumcrot, NC Huston, JC Tycko… - US Patent App. 16 …, 2019 - Google Patents
Disclosed herein are vectors that targets a dystrophin gene, encoding at least one Cas9
molecule or a Cas9 fusion protein, and at least one gRNA molecule (eg, two gRNA …
molecule or a Cas9 fusion protein, and at least one gRNA molecule (eg, two gRNA …
Genome engineering with type I CRISPR systems in eukaryotic cells
Disclosed herein are Type I Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR)/CRISPR-associated (Cas) system related compositions and methods of using …
(CRISPR)/CRISPR-associated (Cas) system related compositions and methods of using …
Genetic correction of mutated genes
C Gersbach, D Ousterout - US Patent 11,976,307, 2024 - Google Patents
FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
amino-3-phenylpropanoyl] amino]-3-phenylpropanoyl] amino]-4-methylpentanoyl] amino] …
Compositions and methods for epigenome editing
CA Gersbach, I Hilton - US Patent 11,155,796, 2021 - Google Patents
US11155796B2 - Compositions and methods for epigenome editing - Google Patents
US11155796B2 - Compositions and methods for epigenome editing - Google Patents …
US11155796B2 - Compositions and methods for epigenome editing - Google Patents …
Compositions, systems, and methods for epigenetic regulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) gene expression
J Kwon, K Congdon - US Patent 12,098,399, 2024 - Google Patents
2024-01-02 Assigned to TUNE THERAPEUTICS, INC. reassignment TUNE
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …
THERAPEUTICS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …