Multiple myeloma (MM) is typically exemplified by a desynchronized cytokine system with
increased levels of inflammatory cytokines. We focused on the contrast between …

The clinical application of rituximab (chimeric mouse anti-human CD20 mAb, Rituxan, IDEC-
C2B8), alone and/or combined with chemotherapy, has significantly ameliorated the …

In chronic lymphocytic leukemia (CLL), acquired T-cell dysfunction impedes development of
effective immunotherapeutic strategies, through as-yet unresolved mechanisms. We have …

To examine the impact of tumors on the immune system, we compared global gene
expression profiles of peripheral blood T cells from previously untreated patients with B cell …

Abstract Treatment of patients with non-Hodgkin's lymphoma (NHL) is frequently hampered
by development of chemoresistance. Rituximab is a chimeric mouse antihuman CD20 …

Virally infected cells degrade intracellular viral proteins proteolytically and present the
resulting peptides in association with major histocompatibility complex (MHC) class I …

PURPOSE: To evaluate immunoglobulin heavy chain (IgH) gene rearrangements, cytokines
and chemokines, and infectious agents in primary intraocular B-cell lymphoma (PIOL) cells …

Objective. The anti-inflammatory limb of the immune response is crucial for dampening
inflammation. Spontaneous parturition at term and preterm labor (PTL) are mediated by …

Diagnosis of PIOL can be challenging. It requires a high degree of clinical suspicion and
differential diagnosis includes infectious and non-infectious etiologies particularly the …

The mechanisms whereby malignant cells can elude the recognition of the immune system,
by what is termed 'immunological escape', have attracted major attention of tumor …