Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are closely related conditions
characterized by systemic inflammation, a predominant IL-6 signature, an excellent …

Vascular pathologies underpin and intertwine autoimmune rheumatic diseases and
cardiovascular conditions, and atherosclerosis is increasingly recognized as the leading …

Giant cell arteritis (GCA) is the most common type of primary vasculitis in Western countries.
Polymyalgia rheumatica (PMR) is the second most common inflammatory rheumatic disease …

Giant cell arteritis (GCA) is a common form of primary systemic vasculitis in adults, with no
reliable indicators of prognosis or treatment responses. We used single cell technologies to …

Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are common conditions in older
adults. Their clinical connection has been recognized over time, with many patients …

Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

The term “vasculitis” refers to a group of rare immune‐mediated diseases characterized by
the dysregulated immune system attacking blood vessels located in any organ of the body …

Background and aim Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease
that is common in elderly people. Its classification in the spectrum of autoinflammatory and …

The giant cell arteritis (GCA) pathophysiology is complex and multifactorial, involving a
predisposing genetic background, the role of immune aging and the activation of vascular …

Objective B-cells are present in the inflamed arteries of giant cell arteritis (GCA) patients and
a disturbed B-cell homeostasis is reported in peripheral blood of both GCA and the …