Elevated mRNA expression levels of DLGAP5 are associated with poor prognosis in breast cancer

T Xu, M Dong, H Li, R Zhang, X Li - Oncology letters, 2020 - spandidos-publications.com
Breast cancer is the most commonly diagnosed type of cancer and one of the leading
causes of cancer‑associated mortality in women. In addition, the underlying molecular …

Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification

L Chen, P Jenjaroenpun, AMC Pillai… - Proceedings of the …, 2017 - National Acad Sciences
Robust prognostic gene signatures and therapeutic targets are difficult to derive from
expression profiling because of the significant heterogeneity within breast cancer (BC) …

The WYL Domain of the PIF1 Helicase from the Thermophilic Bacterium Thermotoga elfii is an Accessory Single-Stranded DNA Binding Module

NM Andis, CW Sausen, A Alladin, ML Bochman - Biochemistry, 2018 - ACS Publications
PIF1 family helicases are conserved from bacteria to man. With the exception of the well-
studied yeast PIF1 helicases (eg, ScPif1 and ScRrm3), however, very little is known about …

ABI1‐based expression signature predicts breast cancer metastasis and survival

A Regua, C Papp, A Grageda, BA Porter… - Molecular …, 2022 - Wiley Online Library
Despite the current standard of care, breast cancer remains one of the leading causes of
mortality in women worldwide, thus emphasizing the need for better predictive and …

Comprehensive tissue-specific gene set enrichment analysis and transcription factor analysis of breast cancer by integrating 14 gene expression datasets

WX Li, K He, L Tang, SX Dai, GH Li, WW Lv… - …, 2016 - pmc.ncbi.nlm.nih.gov
Breast cancer is the most commonly diagnosed malignancy in women. Several key genes
and pathways have been proven to correlate with breast cancer pathology. This study …

The clinical and genetic features in patients coexisting primary breast and thyroid cancers

J Fu, M He, Q Wu, X Zhang, X Qi, K Shen… - Frontiers in …, 2023 - frontiersin.org
Background We attempted to examine the clinical characteristics in patients with breast
cancer (BC) and thyroid cancer (TC); explore the potential mechanisms of tumorigenesis …

Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

L Kalinkova, I Zmetakova, B Smolkova, G Minarik… - BMC cancer, 2018 - Springer
Background In breast cancer (BC), deregulation of DNA methylation leads to aberrant
expressions and functions of key regulatory genes. In our study, we investigated the …

[HTML][HTML] KDM7A-DT induces genotoxic stress, tumorigenesis, and progression of p53 missense mutation-associated invasive breast cancer

A Giannakakis, M Tsifintaris, V Gouzouasis… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Stress-induced promoter-associated and antisense lncRNAs (si-paancRNAs) originate from
a reservoir of oxidative stress (OS)-specific promoters via RNAPII pausing-mediated …

Screening of core genes and pathways in breast cancer development via comprehensive analysis of multi gene expression datasets

J Bai, X Zhang, X Kang, L Jin, P Wang… - Oncology …, 2019 - spandidos-publications.com
Breast cancer has been the leading cause of cancer‑associated mortality in women
worldwide. Perturbation of oncogene and tumor suppressor gene expression is generally …

Identification of recurrent chromosome breaks underlying structural rearrangements in mammary cancer cell lines

NC Senter, A McCulley, VA Kuznetsov, W Feng - Genes, 2022 - mdpi.com
Cancer genomes are characterized by the accumulation of small-scale somatic mutations as
well as large-scale chromosomal deletions, amplifications, and complex structural …