[HTML][HTML] Why patients with familial hypercholesterolemia are at high cardiovascular risk? Beyond LDL-C levels

V Bianconi, M Banach, M Pirro, ILE Panel - Trends in Cardiovascular …, 2021 - Elsevier
Familial hypercholesterolemia (FH) is a common genetic cause of elevated low-density
lipoprotein cholesterol (LDL-C) due to defective clearance of circulating LDL particles. All FH …

[HTML][HTML] Familial hypercholesterolemia in Southeast and East Asia

CL Jackson, M Zordok, IJ Kullo - American Journal of Preventive …, 2021 - Elsevier
Familial hypercholesterolemia (FH) is a relatively common autosomal dominant disorder
associated with a significantly increased risk of coronary heart disease (CHD). Most (~ 85 …

[HTML][HTML] Validity and reliability of an adapted questionnaire measuring knowledge, awareness and practice regarding familial hypercholesterolaemia among primary …

AB Azraii, AS Ramli, Z Ismail, S Abdul-Razak… - BMC cardiovascular …, 2021 - Springer
Background Primary care physicians (PCP) play an important role in detecting Familial
Hypercholesterolaemia (FH) early. However, knowledge, awareness and practice (KAP) …

[HTML][HTML] The M ala y sian HE alth and Well B eing A ssessmen T (MyHEBAT) Study Protocol: An Initiation of a National Registry for Extended Cardiovascular Risk …

AY Firus Khan, AS Ramli, S Abdul Razak… - International Journal of …, 2022 - mdpi.com
Cardiovascular disease (CVD) has been a burden to many developing countries for
decades, including Malaysia. Although various steps have been taken to prevent and …

[HTML][HTML] Familial hypercholesterolaemia and coronary risk factors among patients with angiogram-proven premature coronary artery disease in an Asian cohort

SA Nazli, YA Chua, NA Mohd Kasim, Z Ismail… - Plos one, 2022 - journals.plos.org
Background Familial hypercholesterolaemia (FH) patients have elevated levels of low-
density lipoprotein cholesterol, rendering them at high risk of premature coronary artery …

[HTML][HTML] Genetic spectrum of familial hypercholesterolaemia in the malaysian community: Identification of pathogenic gene variants using targeted next-generation …

AZ Razman, YA Chua, NA Mohd Kasim… - International Journal of …, 2022 - mdpi.com
Familial hypercholesterolaemia (FH) is caused by mutations in lipid metabolism genes,
predominantly in low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB) …

Knowledge, awareness and practice regarding familial hypercholesterolaemia among primary care physicians in Malaysia: The importance of professional training

AB Azraii, AS Ramli, Z Ismail, S Abdul-Razak… - Atherosclerosis, 2018 - Elsevier
Background and aims This study aimed to determine knowledge, awareness and practice
(KAP) regarding familial hypercholesterolaemia (FH) among Malaysian primary care …

[HTML][HTML] Reducing premature coronary artery disease in Malaysia by early identification of familial hypercholesterolemia using the Familial Hypercholesterolemia …

AS Ramli, N Qureshi, H Abdul-Hamid… - JMIR Research …, 2023 - researchprotocols.org
Background: Familial hypercholesterolemia (FH) is predominantly caused by mutations in
the 4 FH candidate genes (FHCGs), namely, low-density lipoprotein receptor (LDLR) …

[HTML][HTML] A global review on the utility of genetic testing for familial hypercholesterolemia

RM Hendricks-Sturrup, J Clark-LoCascio… - Journal of Personalized …, 2020 - mdpi.com
Familial hypercholesterolemia (FH) is a genetic disorder of cholesterol metabolism that
affects an estimated 1/250 persons in the United States and abroad. FH is hallmarked by …

Autosomal dominant hypercholesterolemia in Catalonia: Correspondence between clinical-biochemical and genetic diagnostics in 967 patients studied in a …

JM Martín-Campos, N Plana, R Figueras… - Journal of Clinical …, 2018 - Elsevier
Background Autosomal dominant hypercholesterolemia (ADH) is associated with mutations
in the low-density lipoprotein (LDL) receptor (LDLR), apolipoprotein B (APOB), and …