Chromatin structure in totipotent mouse early preimplantation embryos

M Ooga - Journal of Reproduction and Development, 2024 - jstage.jst.go.jp
Totipotency refers to the ability of a single cell to give rise to all the different cell types in the
body. Terminally differentiated germ cells (sperm and oocytes) undergo reprogramming …

Embryoids, models, embryos? We need to take a new look at legal norms concerning the beginning of organismic development

HW Denker - Molecular Human Reproduction, 2024 - academic.oup.com
The recent progress in research on embryo-like structures (ELS) derived in vitro from
pluripotent stem cells is impressive (Amadei et al., 2022; Rossant and Tam, 2022; Tarazi et …

The explosive discovery of TNT in early mouse embryos

CS Driscoll, J Kim, JG Knott - Nature Structural & Molecular Biology, 2024 - nature.com
The molecular mechanisms that regulate the transition from totipotency into divergent
cellular states are unclear. Two new studies show that the transcription factors TFAP2C …

[HTML][HTML] Stem Cell-Derived Organoids, Embryoids, and Embryos: Advances in Organismic Development In Vitro Force Us to Re-Focus on Ethical and Legal Aspects of …

HW Denker - Organoids, 2023 - mdpi.com
While research on stem cell-derived tissues and organoids is rapidly expanding, the
technically related creation of complex embryoids has recently excited a vivid discussion …