Fusobacterium nucleatum and cancer

T Alon‐Maimon, O Mandelboim… - Periodontology …, 2022 - Wiley Online Library
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is
involved in the progression of an increasing number of tumors types. Thus far, the …

[HTML][HTML] Role of the tumor microenvironment in cancer hallmarks and targeted therapy

R Naser, I Fakhoury, A El-Fouani… - International …, 2022 - spandidos-publications.com
Genetic alterations drive tumor onset and progression. However, the cross-talk between
tumor cells and the benign components of the surrounding stroma can also promote the …

[HTML][HTML] Tumor microbiome metabolism: A game changer in cancer development and therapy

X Zhou, S Kandalai, F Hossain, Q Zheng - Frontiers in Oncology, 2022 - frontiersin.org
Accumulating recent evidence indicates that the human microbiome plays essential roles in
pathophysiological states, including cancer. The tumor microbiome, an emerging concept …

[HTML][HTML] Intratumoral microbiome of human primary liver cancer

D Qu, Y Wang, Q Xia, J Chang, X Jiang… - Hepatology …, 2022 - journals.lww.com
Primary liver tumors (PLCs) and liver metastasis currently represent the leading cause of
cancer‐related deaths worldwide due to poor outcomes, high incidence, and postsurgical …

Local tumor microbial signatures and response to checkpoint blockade in non-small cell lung cancer

M Boesch, F Baty, WC Albrich, L Flatz… - …, 2021 - Taylor & Francis
In cancer patients, the clinical response to checkpoint-based immunotherapy is associated
with the composition and functional quality of the host microbiome. While the relevance of …

Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

S Meza-Perez, M Liu, A Silva-Sanchez, CD Morrow… - Cell Host & Microbe, 2024 - cell.com
Gut microbiota influence anti-tumor immunity, often by producing immune-modulating
metabolites. However, microbes consume a variety of metabolites that may also impact host …

[HTML][HTML] Bacterial infection and microbiota in carcinogenesis and tumor development

Q Li - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
Microbiota colonize exposed body tissues (eg, gastrointestinal tract, skin, lungs, female
genital tract, and urogenital tracts) and unexposed sites (eg, breast). Persistent bacterial …

Targeting butyrophilins for cancer immunotherapy

M Rigau, AP Uldrich, A Behren - Trends in immunology, 2021 - cell.com
Vγ9Vδ2+ T cells form part of the innate immune repertoire and are activated by
phosphorylated antigens produced by many bacteria and tumors. They have long been …

[HTML][HTML] The machine-learning-mediated interface of microbiome and genetic risk stratification in neuroblastoma reveals molecular pathways related to patient survival

X Li, X Wang, R Huang, A Stucky, X Chen, L Sun… - Cancers, 2022 - mdpi.com
Simple Summary Neuroblastoma is a highly heterogeneous malignancy with a wide range
of outcomes from spontaneous regression to fatal chemoresistant disease, as currently …

[HTML][HTML] Bacterial Therapy of Cancer: A Way to the Dustbin of History or to the Medicine of the Future?

LN Ikryannikova, NV Gorokhovets, DA Belykh… - International Journal of …, 2023 - mdpi.com
Bacteria are the constant companions of the human body throughout its life and even after
its death. The history of a human disease such as cancer and the history of microorganisms …