[HTML][HTML] Biomaterial-induced pathway modulation for bone regeneration
Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …
Production and utility of extracellular vesicles with 3D culture methods
M Casajuana Ester, RM Day - Pharmaceutics, 2023 - mdpi.com
In recent years, extracellular vesicles (EVs) have emerged as promising biomarkers, cell-
free therapeutic agents, and drug delivery carriers. Despite their great clinical potential, poor …
free therapeutic agents, and drug delivery carriers. Despite their great clinical potential, poor …
Controlled release of epigenetically-enhanced extracellular vesicles from a GelMA/nanoclay composite hydrogel to promote bone repair
Extracellular vesicles (EVs) have garnered growing attention as promising acellular tools for
bone repair. Although EVs' potential for bone regeneration has been shown, issues …
bone repair. Although EVs' potential for bone regeneration has been shown, issues …
Surface functionalization of titanium-based implants with a nanohydroxyapatite layer and its impact on osteoblasts: a systematic review
K Homa, W Zakrzewski, W Dobrzyński… - Journal of Functional …, 2024 - mdpi.com
This study aims to evaluate the influence of a nanohydroxyapatite layer applied to the
surface of titanium or titanium alloy implants on the intricate process of osseointegration and …
surface of titanium or titanium alloy implants on the intricate process of osseointegration and …
An ECM-mimetic hydrogel to promote the therapeutic efficacy of osteoblast-derived extracellular vesicles for bone regeneration
The use of extracellular vesicles (EVs) is emerging as a promising acellular approach for
bone regeneration, overcoming translational hurdles associated with cell-based therapies …
bone regeneration, overcoming translational hurdles associated with cell-based therapies …
[HTML][HTML] Phase selection-oriented mechanical properties tailoring for β-type TiNbZrTaSi alloy fabricated by laser powder bed fusion
The morphology and distribution of silicides in α/α+ β type titanium alloys impress on their
properties. Nevertheless, the types of silicide precipitates and their formation mechanisms …
properties. Nevertheless, the types of silicide precipitates and their formation mechanisms …
Epigenetic reprogramming via synergistic hypomethylation and hypoxia enhances the therapeutic efficacy of mesenchymal stem cell extracellular vesicles for bone …
Mesenchymal stem cells (MSCs) are a promising cell population for regenerative medicine
applications, where paracrine signalling through the extracellular vesicles (EVs) regulates …
applications, where paracrine signalling through the extracellular vesicles (EVs) regulates …
Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192
Epigenetics plays a critical role in regulating mesenchymal stem cells'(MSCs) fate for tissue
repair and regeneration. There is increasing evidence that the inhibition of histone …
repair and regeneration. There is increasing evidence that the inhibition of histone …
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanism
Blood vessel formation is an important initial step for bone formation during development as
well as during remodelling and repair in the adult skeleton. This results in a heavily …
well as during remodelling and repair in the adult skeleton. This results in a heavily …
Bioengineering extracellular vesicles: smart nanomaterials for bone regeneration
In the past decade, extracellular vesicles (EVs) have emerged as key regulators of bone
development, homeostasis and repair. EV-based therapies have the potential to …
development, homeostasis and repair. EV-based therapies have the potential to …