Type 2 diabetes mellitus-associated cognitive dysfunction: advances in potential mechanisms and therapies

A Luo, Z Xie, Y Wang, X Wang, S Li, J Yan… - Neuroscience & …, 2022 - Elsevier
Abstract Type 2 diabetes (T2D) and its target organ injuries cause distressing impacts on
personal health and put an enormous burden on the healthcare system, and increasing …

Relationship between type 2 diabetes and white matter hyperintensity: a systematic review

DQ Wang, L Wang, MM Wei, XS Xia, XL Tian… - Frontiers in …, 2020 - frontiersin.org
White matter (WM) disease is recognized as an important cause of cognitive decline and
dementia. White matter lesions (WMLs) appear as white matter hyperintensities (WMH) on …

Effect of linagliptin on cognitive performance in patients with type 2 diabetes and cardiorenal comorbidities: the CARMELINA randomized trial

GJ Biessels, C Verhagen, J Janssen… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE Type 2 diabetes is associated with cognitive dysfunction and an increased
dementia risk, particularly in individuals with concomitant cardiovascular and/or kidney …

Albuminuria as a risk factor for mild cognitive impairment and dementia—what is the evidence?

B Bikbov, MJ Soler, V Pešić, G Capasso… - Nephrology Dialysis …, 2022 - academic.oup.com
Kidney dysfunction can profoundly influence many organ systems, and recent evidence
suggests a potential role for increased albuminuria in the development of mild cognitive …

Association of kidney function measures with signs of neurodegeneration and small vessel disease on brain magnetic resonance imaging: the Atherosclerosis Risk in …

JB Scheppach, A Wu, RF Gottesman, TH Mosley… - American Journal of …, 2023 - Elsevier
Rationale & Objective Chronic kidney disease (CKD) is a risk factor for cognitive decline, but
evidence is limited on its etiology and morphological manifestation in the brain. We …

Cognitive protection of incretin‐based therapies in patients with type 2 diabetes mellitus: A systematic review and meta‐analysis based on clinical studies

S Chai, F Liu, S Yu, Z Yang… - Journal of Diabetes …, 2023 - Wiley Online Library
Aims/introduction Cognitive dysfunction, including mild cognitive impairment and dementia,
is increasingly recognized as an important complication of type 2 diabetes mellitus. The …

Prevalence and risk of severe cognitive impairment in advanced chronic kidney disease

CM Burns, DS Knopman, DE Tupper… - The Journals of …, 2018 - academic.oup.com
Background Our primary goal is to describe the prevalence, severity, and risk of cognitive
impairment (CI) by estimated glomerular filtration rate (eGFR, in mL/min/1.73 m2) in a cohort …

Diabetes, Albuminuria and the Kidney—Brain Axis

DM Ariton, J Jiménez-Balado, O Maisterra… - Journal of clinical …, 2021 - mdpi.com
Cognitive decline and kidney disease are significant public health problems that share
similar characteristics and risk factors. The pathophysiology of the kidney–brain axis is not …

Transcultural diabetes care in the United States–a position statement by the American Association of Clinical Endocrinologists

JI Mechanick, S Adams, JA Davidson, IV Fergus… - Endocrine Practice, 2019 - Elsevier
ABSTRACT The American Association of Clinical Endocrinologists (AACE) has created a
transculturalized diabetes chronic disease care model that is adapted for patients across a …

CKD, brain atrophy, and white matter lesion volume: The Japan prospective studies collaboration for aging and dementia

K Maki, T Ohara, J Hata, M Shibata, N Hirabayashi… - Kidney Medicine, 2023 - Elsevier
Rationale & Objective Chronic kidney disease, defined by albuminuria and/or reduced
estimated glomerular filtration rate (eGFR), has been reported to be associated with brain …