Sepsis is defined as organ dysfunction resulting from the host's deleterious response to
infection. One of the most common organs affected is the kidneys, resulting in sepsis …

Sepsis is a dysregulated immune response to an infection that leads to organ dysfunction.
Knowledge of the pathophysiology of organ failure in sepsis is crucial for optimizing the …

Acute kidney injury (AKI) and sepsis carry consensus definitions. The simultaneous
presence of both identifies septic AKI. Septic AKI is the most common AKI syndrome in ICU …

Acute kidney injury (AKI) is a multifaceted syndrome that occurs in different settings. The
course of AKI can be variable, from single hit and complete recovery, to multiple hits …

Importance Sepsis-associated acute kidney injury (AKI) adversely affects long-term kidney
outcomes and survival. Administration of the detoxifying enzyme alkaline phosphatase may …

Background Acute kidney injury occurs in one in four children admitted to an intensive care
unit (ICU) and its severity is independently associated with increased patient morbidity and …

In recent years, much new data on intestinal alkaline phosphatase (IAP) have been
published, and major breakthroughs have been disclosed. The aim of the present review is …

Alkaline phosphatase can be considered “our favorite enzyme” for reasons apparent to
those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few …

Sepsis is a heterogenous and highly complex clinical syndrome, which is caused by
infectious or noninfectious factors. Acute kidney injury (AKI) is one of the most common and …

Acute kidney injury (AKI) is a common disease with a complex pathophysiology. The old
paradigm of identifying renal injury based on location—prerenal, intrarenal, and postrenal …