Abstract αKlotho (called Klotho here) is a membrane protein that serves as the coreceptor for
the circulating hormone fibroblast growth factor 23 (FGF23). Klotho is also cleaved and …

Burns are a seriously underestimated form of trauma that not only damage the skin system
but also cause various complications, such as acute kidney injury (AKI). Recent clinical …

Kidneys are highly vascular organs that despite their relatively small size receive 20% of the
cardiac output. The highly intricate, delicately organized structure of renal microcirculation is …

Acute kidney injury (AKI) is a strong independent predictor of mortality and often results in
incomplete recovery of renal function, leading to progressive chronic kidney disease (CKD) …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are the most severe
consequences of kidney injury. They are interconnected syndromes as CKD predisposes to …

Aberrant lymphatic system function has been increasingly implicated in pathologies such as
lymphedema, organ transplant rejection, cardiovascular disease, obesity, and …

Inflammation that develops with the release of chemokines and cytokines during acute
kidney injury (AKI) has been shown to participate in functional renal recovery. Although a …

Acute kidney injury (AKI) management remains mainly supportive as no specific therapeutic
agents directed at singular signaling pathways have succeeded in clinical trials. Here, we …

After the severe initial insults of acute kidney injury, progressive kidney tubulointerstitial
fibrosis may occur, the peritubular capillary (PTC) rarefaction plays a key role in the disease …

Background: Elevated plasma C-terminal fibroblast growth factor-23 (cFGF-23) levels are
associated with higher mortality in patients with chronic kidney disease (CKD) and acute …