ICAM-1 and VCAM-1: Gatekeepers in various inflammatory and cardiovascular disorders

V Singh, R Kaur, P Kumari, C Pasricha, R Singh - Clinica Chimica Acta, 2023 - Elsevier
Leukocyte migration from the vascular compartment is critical for normal lymphocyte
recirculation in specific tissues and immune response in inflammatory locations. Leukocyte …

Glycolysis rate-limiting enzymes: novel potential regulators of rheumatoid arthritis pathogenesis

J Zuo, J Tang, M Lu, Z Zhou, Y Li, H Tian, E Liu… - Frontiers in …, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a classic autoimmune disease characterized by uncontrolled
synovial proliferation, pannus formation, cartilage injury, and bone destruction. The specific …

Efficacy, safety, pharmacokinetics, and pharmacodynamics of filgotinib, a selective JAK‐1 inhibitor, after short‐term treatment of rheumatoid arthritis: results of two …

F Vanhoutte, M Mazur, O Voloshyn… - Arthritis & …, 2017 - Wiley Online Library
Objective JAK inhibitors have shown efficacy in rheumatoid arthritis (RA). We undertook this
study to test our hypothesis that selective inhibition of JAK‐1 would combine good efficacy …

New insights to the mechanisms underlying atherosclerosis in rheumatoid arthritis

M Mahmoudi, S Aslani, R Fadaei… - International journal of …, 2017 - Wiley Online Library
Rheumatoid arthritis (RA) is an inflammatory circumstance, which has been associated with
increased risk of cardiovascular disease (CVD). Although RA management has been …

[HTML][HTML] Circulating soluble ICAM-1 and subclinical atherosclerosis: The coronary artery risk development in young adults (CARDIA) study

MD Gross, SJ Bielinski, JR Suarez-Lopez… - Clinical …, 2012 - ncbi.nlm.nih.gov
Background Soluble intercellular adhesion molecule-1 (sICAM-1) is associated with
endothelial dysfunction and clinical cardiovascular disease. We investigated the relationship …

Ischemic heart disease and rheumatoid arthritis—two conditions, the same background

E Rezuș, LA Macovei, AM Burlui, A Cardoneanu… - Life, 2021 - mdpi.com
Rheumatoid arthritis (RA) is one of the most frequent inflammatory rheumatic diseases,
having a considerably increased prevalence of mortality and morbidity due to cardiovascular …

Circulating soluble intercellular adhesion molecule 1 and subclinical atherosclerosis: the Coronary Artery Risk Development in Young Adults Study

MD Gross, SJ Bielinski, JR Suarez-Lopez… - Clinical …, 2012 - academic.oup.com
BACKGROUND Soluble intercellular adhesion molecule 1 (sICAM-1) is associated with
endothelial dysfunction and clinical cardiovascular disease. We investigated the relationship …

[HTML][HTML] VCAM-1 is a TGF-β1 inducible gene upregulated in idiopathic pulmonary fibrosis

M Agassandian, JR Tedrow, J Sembrat, DJ Kass… - Cellular signalling, 2015 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a chronic lethal interstitial lung disease of unknown
etiology. We previously reported that high plasma levels of vascular cell adhesion molecule …

Elevated VCAM-1, MCP-1 and ADMA serum levels related to pulmonary fibrosis of interstitial lung disease associated with rheumatoid arthritis

V Pulito-Cueto, S Remuzgo-Martínez… - Frontiers in molecular …, 2022 - frontiersin.org
Introduction: Early diagnosis of interstitial lung disease (ILD) associated with rheumatoid
arthritis (RA) constitutes a challenge for the clinicians. Pulmonary vasculopathy is relevant in …

Cardiovascular risk in rheumatoid arthritis: how to lower the risk?

DF Van Breukelen-van der Stoep, B Klop, D van Zeben… - Atherosclerosis, 2013 - Elsevier
Patients with rheumatoid arthritis (RA) carry an excess risk for cardiovascular disease, which
is comparable to the risk in patients with type 2 diabetes mellitus. The mechanisms involved …