Acute otitis media and otitis media with effusion are common childhood disorders, a source
of significant morbidity, and a leading cause of antibiotic prescription in primary health care …

Background Infection with Streptococcus pneumoniae is a major cause of childhood
morbidity and mortality worldwide, especially in low income countries where pneumococcal …

The upper respiratory tract (URT) is a crucial site for host defense, as it is home to bacterial
communities that both modulate host immune defense and serve as a reservoir of potential …

Abstract In March 2010, Brazil introduced the 10-valent pneumococcal conjugate vaccine
(PCV10) in the routine infant immunization program using a 4-dose schedule and catch-up …

After introduction of the 7-valent pneumococcal conjugate vaccine (PCV7) in the infant
national immunization program (NIP) in the Netherlands in 2006, Streptococcus …

Streptococcus pneumoniae is an important cause of infection and commonly colonizes the
nasopharynx of young children, along with other potentially pathogenic bacteria. The …

Objectives This study aims to monitor the prevalence of suppurative otitis media in remote
Indigenous communities after introduction of 13-valent pneumococcal conjugate vaccine …

Objective To evaluate the carriage prevalence, serotype distribution, and antibiotic
resistance for pneumococcal carriage isolates collected 4–8 years after introduction of …

Biofilm-associated infections are of great concern because they are associated with
antibiotic resistance and immune evasion. Co-colonization by Staphylococcus aureus and …

A chronic disease in older adults usually runs a course that is less predictable than in
younger individuals. Unexplained variations in disease incidence, prognosis, therapeutic …