Plant Protein Resources, Novel Extraction and Precipitation Methods: A Review

A Akyüz, İ Tekin, Z Aksoy… - Journal of Food Process …, 2024 - Wiley Online Library
This comprehensive review explores the diverse landscape of plant protein resources,
focusing on novel extraction and precipitation methods that contribute to the advancement of …

Optimizing particle morphology during antibody precipitation for enhanced tangential flow filtration performance

M Minervini, A Behboudi, JR Marzella… - Separation and …, 2024 - Elsevier
Recent advances in cell culture have led to substantial increases in monoclonal antibody
titer, leading to renewed interest in using precipitation for the initial capture and purification …

[HTML][HTML] Solving crystallization/precipitation population balance models in CADET, Part II: Size-based Smoluchowski coagulation and fragmentation equations in batch …

W Zhang, T Przybycien, JM Breuer… - Computers & Chemical …, 2025 - Elsevier
A particle size-based Smoluchowski coagulation and fragmentation equation was solved in
the free and open source process modeling package CADET. The WFV and MCNP …

Combining descriptive and predictive modeling to systematically design depth filtration‐based harvest processes for biologics

P Liu, M Hartmann, A Shankaran, H Li… - Biotechnology and …, 2024 - Wiley Online Library
Advances in upstream production of biologics–particularly intensified fed‐batch processes
beyond 10% cell solids–have severely strained harvest operations, especially depth …

[HTML][HTML] A Precipitation-Based Process to Generate a Solid Formulation of a Therapeutic Monoclonal Antibody: An Alternative to Lyophilization

AA Koynov, W Lin, JR Bothe, L Schenck… - … of Pharmaceutical and …, 2025 - mdpi.com
Lyophilization, or freeze-drying, is the default technique for the manufacture of solid-state
formulations of therapeutic proteins. This established method offers several advantages …

Removal of Residual DNA and Host Cell Proteins for the Purification of Recombinant Staphylokinase Expressed in Escherichia coli

L Guang, L jing, Z Zhenxing, L Bo… - Separation …, 2024 - Wiley Online Library
The elimination of residual host cell DNA (HCD) and proteins (HCPs) is a pivotal step in the
purification process for biological products such as monoclonal antibodies, recombinant …

Precipitation-Filtration Process as a Platform for Continuous Purification of Monoclonal Antibody Therapeutics

M Minervini - 2024 - search.proquest.com
The significant increase in product titers, coupled with the growing focus on continuous
bioprocessing, has renewed interest in using target precipitation as a low‐cost alternative to …