Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

Iron oxide based nanoparticles for multimodal imaging and magnetoresponsive therapy

N Lee, D Yoo, D Ling, MH Cho, T Hyeon… - Chemical …, 2015 - ACS Publications
Magnetic nanoparticles have received tremendous attention in diverse fields because of
their unique nanoscale physicochemical properties and the potential for a wide range of …

Magnetic nanoparticle facilitated drug delivery for cancer therapy with targeted and image‐guided approaches

J Huang, Y Li, A Orza, Q Lu, P Guo… - Advanced functional …, 2016 - Wiley Online Library
With rapid advances in nanomedicine, magnetic nanoparticles (MNPs) have emerged as a
promising theranostic tool in biomedical applications, including diagnostic imaging, drug …

Exerting Enhanced Permeability and Retention Effect Driven Delivery by Ultrafine Iron Oxide Nanoparticles with T1T2 Switchable Magnetic Resonance Imaging …

L Wang, J Huang, H Chen, H Wu, Y Xu, Y Li, H Yi… - Acs Nano, 2017 - ACS Publications
Poor delivery efficiency remains a major challenge in nanomaterial-based tumor-targeted
imaging and drug delivery. This work demonstrates a strategy to improve nanoparticle …

Theranostic nanoparticles with controlled release of gemcitabine for targeted therapy and MRI of pancreatic cancer

GY Lee, WP Qian, L Wang, YA Wang, CA Staley… - ACS …, 2013 - ACS Publications
The tumor stroma in human cancers significantly limits the delivery of therapeutic agents into
cancer cells. To develop an effective therapeutic approach overcoming the physical barrier …

[HTML][HTML] Improving the magnetic resonance imaging contrast and detection methods with engineered magnetic nanoparticles

J Huang, X Zhong, L Wang, L Yang, H Mao - Theranostics, 2012 - ncbi.nlm.nih.gov
Engineering and functionalizing magnetic nanoparticles have been an area of the extensive
research and development in the biomedical and nanomedicine fields. Because their …

Urchin‐Shaped Manganese Oxide Nanoparticles as pH‐Responsive Activatable T1 Contrast Agents for Magnetic Resonance Imaging

T Kim, EJ Cho, Y Chae, M Kim, A Oh, J Jin… - Angewandte Chemie …, 2011 - infona.pl
Image enhancement: Core–shell MnO@ Mn 3 O 4 urchin‐shaped nanoparticles can be
synthesized by means of an anisotropic etching process and used as a pH‐activatable T 1 …

Application of nanoparticles on diagnosis and therapy in gliomas

NY Hernández-Pedro, E Rangel-López… - BioMed research …, 2013 - Wiley Online Library
Glioblastoma multiforme (GBM) is one of the most deadly diseases that affect humans, and it
is characterized by high resistance to chemotherapy and radiotherapy. Its median survival is …

Facile non-hydrothermal synthesis of oligosaccharide coated sub-5 nm magnetic iron oxide nanoparticles with dual MRI contrast enhancement effects

J Huang, L Wang, X Zhong, Y Li, L Yang… - Journal of Materials …, 2014 - pubs.rsc.org
Ultrafine sub-5 nm magnetic iron oxide nanoparticles coated with oligosaccharides (SIO)
with dual T1–T2 weighted contrast enhancing effects and fast clearance have been …

Ultracompact Iron Oxide Nanoparticles with a Monolayer Coating of Succinylated Heparin: A New Class of Renal-Clearable and Nontoxic T1 Agents for High-Field …

M Xie, Z Wang, Q Lu, S Nie, CJ Butch… - … applied materials & …, 2020 - ACS Publications
Herein, we present a new magnetic iron oxide nanoparticle (MION) with a succinylated
heparin monolayer coating, which exhibits the highest T1 relaxivity at 7 T and the lowest r 2/r …