The continuous degradation and synthesis of prokaryotic mRNAs not only give rise to the
metabolic changes that are required as cells grow and divide but also rapid adaptation to …

The diversity of RNAs in the cell continues to amaze. In addition to the 'classic'species of
mRNA, tRNA, rRNA, snRNA and snoRNA, it is now clear that the majority of genomic …

To characterize MDa-sized macromolecular chloroplast stroma protein assemblies and to
extend coverage of the chloroplast stroma proteome, we fractionated soluble chloroplast …

Intra-plastid proteases play crucial and diverse roles in the development and maintenance
of non-photosynthetic plastids and chloroplasts. Formation and maintenance of a functional …

The clpr2-1 mutant is delayed in development due to reduction of the chloroplast ClpPR
protease complex. To understand the role of Clp proteases in plastid biogenesis and …

The transient existence of small RNAs free of binding to the RNA chaperone Hfq is part of
the normal dynamic lifecycle of a sRNA. Small RNAs are extremely labile when not …

Background The RNA steady-state levels in the cell are a balance between synthesis and
degradation rates. Although transcription is important, RNA processing and turnover are …

Defective RNAs and proteins are swiftly degraded by cellular quality control mechanisms. A
large fraction of their degradation is mediated by the exosome and the proteasome. These …

RNA degradation is a major process controlling RNA levels and plays a central role in cell
metabolism. From the labile messenger RNA to the more stable noncoding RNAs (mostly …

Although the first poly (A) polymerase (PAP) was discovered in Escherichia coli in 1962, the
study of polyadenylation in bacteria was largely ignored for the next 30 years. However, with …