Drug addiction is a devastating condition that poses a serious burden on the society. The
use of some drugs like morphine for their tremendous analgesic properties is also …

Chronic pain is a common cause of disability worldwide and remains a global health and
socio‐economic challenge. Current analgesics are either ineffective in a significant …

Multiple sclerosis (MS) is a debilitating, inflammatory, and demyelinating disease of the
central nervous system influenced by environmental and genetic factors. Around 2.8 million …

Chronic pain is an important health and social problem. Misuse and abuse of opioids in
chronic non-cancer pain management seem to be a huge problem, in some countries. This …

This paper is the thirty-eighth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2015 …

Opioids are the most effective drugs used for the management of moderate to severe pain;
however, their chronic use is often associated with numerous adverse effects. Some results …

Background The underlying mechanism of Parkinson's disease are still unidentified, but
excitotoxicity, oxidative stress, and neuroinflammation are considered key actors. Proliferator …

As manifestations of excessive and uncontrolled intake, obesity and drug addiction have
generated much research aimed at identifying common neuroadaptations that could …

A growing body of research indicates that β-caryophyllene (BCP), a constituent present in a
large number of plants, possesses significant therapeutic properties against CNS disorders …

Introduction Pain is a multidimensional experience involving the biological, psychological,
and social dimensions of each individual. Particularly, the biological aspects of pain …