Novel insights into immune systems of bats
In recent years, viruses similar to those that cause serious disease in humans and other
mammals have been detected in apparently healthy bats. These include filoviruses …
mammals have been detected in apparently healthy bats. These include filoviruses …
[HTML][HTML] The world goes bats: living longer and tolerating viruses
For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …
[HTML][HTML] Zoonotic disease and virome diversity in bats
K Van Brussel, EC Holmes - Current Opinion in Virology, 2022 - Elsevier
The emergence of zoonotic viral diseases in humans commonly reflects exposure to
mammalian wildlife. Bats (order Chiroptera) are arguably the most important mammalian …
mammalian wildlife. Bats (order Chiroptera) are arguably the most important mammalian …
[HTML][HTML] Bat pluripotent stem cells reveal unusual entanglement between host and viruses
Bats are distinctive among mammals due to their ability to fly, use laryngeal echolocation,
and tolerate viruses. However, there are currently no reliable cellular models for studying bat …
and tolerate viruses. However, there are currently no reliable cellular models for studying bat …
Accelerated viral dynamics in bat cell lines, with implications for zoonotic emergence
Bats host virulent zoonotic viruses without experiencing disease. A mechanistic
understanding of the impact of bats' virus hosting capacities, including uniquely constitutive …
understanding of the impact of bats' virus hosting capacities, including uniquely constitutive …
Alternative animal models of aging research
S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …
Bat biology, genomes, and the Bat1K project: to generate chromosome-level genomes for all living bat species
Bats are unique among mammals, possessing some of the rarest mammalian adaptations,
including true self-powered flight, laryngeal echolocation, exceptional longevity, unique …
including true self-powered flight, laryngeal echolocation, exceptional longevity, unique …
Going to bat (s) for studies of disease tolerance
A majority of viruses that have caused recent epidemics with high lethality rates in people,
are zoonoses originating from wildlife. Among them are filoviruses (eg, Marburg, Ebola) …
are zoonoses originating from wildlife. Among them are filoviruses (eg, Marburg, Ebola) …
Combining antivirals and immunomodulators to fight COVID-19
V Feuillet, B Canard, A Trautmann - Trends in immunology, 2021 - cell.com
The majority of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected
individuals remain paucisymptomatic, contrasting with a minority of infected individuals in …
individuals remain paucisymptomatic, contrasting with a minority of infected individuals in …
Large‐scale genome sampling reveals unique immunity and metabolic adaptations in bats
DD Moreno Santillán, TM Lama… - Molecular …, 2021 - Wiley Online Library
Abstract Comprising more than 1,400 species, bats possess adaptations unique among
mammals including powered flight, unexpected longevity, and extraordinary immunity. Some …
mammals including powered flight, unexpected longevity, and extraordinary immunity. Some …