Local immune recognition of trophoblast in early human pregnancy: controversies and questions

A Moffett, N Shreeve - Nature Reviews Immunology, 2023 - nature.com
The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …

Innate lymphoid cells: major players in inflammatory diseases

M Ebbo, A Crinier, F Vély, E Vivier - Nature Reviews Immunology, 2017 - nature.com
Recent years have seen a marked increase in our understanding of innate lymphoid cells
(ILCs). ILCs can be classified into different groups based on their similarity to T cell subsets …

Nomenclature of allergic diseases and hypersensitivity reactions: Adapted to modern needs: An EAACI position paper

M Jutel, I Agache, M Zemelka‐Wiacek, M Akdis… - Allergy, 2023 - Wiley Online Library
The exponential growth of precision diagnostic tools, including omic technologies, molecular
diagnostics, sophisticated genetic and epigenetic editing, imaging and nano‐technologies …

ILC3 function as a double-edged sword in inflammatory bowel diseases

B Zeng, S Shi, G Ashworth, C Dong, J Liu, F Xing - Cell death & disease, 2019 - nature.com
Inflammatory bowel diseases (IBD), composed mainly of Crohn's disease (CD) and
ulcerative colitis (UC), are strongly implicated in the development of intestinal inflammation …

Human neutrophils in the saga of cellular heterogeneity: insights and open questions

P Scapini, O Marini, C Tecchio… - Immunological …, 2016 - Wiley Online Library
Recent findings have uncovered novel fascinating aspects of the biology of neutrophils,
which ultimately attribute to these cells a broader role in inflammation and immunity. One …

Innate immune responses to acute viral infection during pregnancy

EF Cornish, I Filipovic, F Åsenius, DJ Williams… - Frontiers in …, 2020 - frontiersin.org
Immunological adaptations in pregnancy allow maternal tolerance of the semi-allogeneic
fetus but also increase maternal susceptibility to infection. At implantation, the endometrial …

Immune responses in the human female reproductive tract

L Monin, EM Whettlock, V Male - Immunology, 2020 - Wiley Online Library
Mucosal surfaces are key interfaces between the host and its environment, but also
constitute ports of entry for numerous pathogens. The gut and lung mucosae act as points of …

Gestational diabetes mellitus and maternal immune dysregulation: what we know so far

CJ McElwain, FP McCarthy, CM McCarthy - International Journal of …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is an obstetric complication that affects approximately 5–
10% of all pregnancies worldwide. GDM is defined as any degree of glucose intolerance …

Immunobiology of acute chorioamnionitis

M Cappelletti, P Presicce, SG Kallapur - Frontiers in immunology, 2020 - frontiersin.org
Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …

Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy

S Nadkarni, J Smith… - Proceedings of the …, 2016 - National Acad Sciences
Although neutrophils are known to be fundamental in controlling innate immune responses,
their role in regulating adaptive immunity is just starting to be appreciated. We report that …