This critical time frame of intrauterine life development is considered of major importance on
the metabolic imprinting of overall health of the offspring, in later life. This requires a delicate …

This review summarizes and integrates research on vitamin D and CD4+ T-lymphocyte
biology to develop new mechanistic insights into the molecular etiology of autoimmune …

Vitamin D is a micronutrient with pleiotropic effects in humans. Due to sedentary lifestyles
and increasing time spent indoors, a growing body of research is revealing that vitamin D …

Vitamin D has well-defined classical functions related to metabolism and bone health but
also has non-classical effects that may influence pregnancy. Maternal morbidity remains a …

Background About 30% of women entering pregnancy in the US are obese. We have
previously reported mitochondrial dysregulation and increased inflammation in the …

The first trimester of pregnancy ranks high in priority when minimizing harmful exposures,
given the wide-ranging types of organogenesis occurring between 4-and 12-weeks' …

Problem Vitamin D has a pivotal role in regulating immune responses in women with
recurrent pregnancy loss (RPL), but the underlying mechanism has not been completely …

Results: By pregnancy/non-gravid, normal pregnant women had higher 25 (OH) D (49.32
μg/l) and CYP27B1 (82.00 pg/ml) than PL women (34.49 μg/l and 37.87 pg/ml, both P< …

Background: Vitamin D and iron deficiencies frequently co-exist. It is now appreciated that
mechanistic interactions between iron and vitamin D metabolism may underlie these …

Multiple sclerosis (MS) is a neurodegenerative disease resulting from an autoimmune attack
on the axon-myelin unit. A female MS bias becomes evident after puberty and female …