Highlights•Sepsis is a life-threatening condition caused by the body's response to an
infection and there is a lack of effective treatments available.•Microvascular dysfunction is …

Many 'non-enveloped'viruses, including hepatitis A virus (HAV), are released non-lytically
from infected cells as infectious, quasi-enveloped virions cloaked in host membranes. Quasi …

Research on human enteroviruses has resulted in the identification of more than 100
enterovirus types, which use more than 10 protein receptors and/or attachment factors …

Identifying best bioactive phytochemicals from different medicinal plants using molecular
docking techniques demonstrates a potential pre-clinical compound discovery against …

Classical plaque assay measures the propagation of infectious agents across a monolayer
of cells. It is dependent on cell lysis, and limited by user-specific settings and low throughput …

Nineteen CVA9 isolates were obtained between 2010 and 2019 from six provinces of
mainland China, using the HFMD surveillance network established in China. Nucleotide …

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that is one of the major
causes of viral encephalitis diseases worldwide. The JEV envelope protein facilitates viral …

Human cerebral microvascular endothelial cells (hCMEC/D3 cell line) form a steady
polarized barrier when cultured in vitro on a permeable membrane. Their susceptibility to …

Human parechovirus 1 (HPeV-1)(family Picornaviridae) is a global cause of pediatric
respiratory and CNS infections for which there is no treatment. Although biochemical and in …

Heparan sulfate/heparin class of proteoglycans (HSPG) have been shown to function in
cellular attachment and infection of numerous viruses including picornaviruses …