Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …

At present, a large number of relevant studies have suggested that the changes in gut
microbiota are related to the course of nervous system diseases, and the microbiota-gut …

Background Dysregulation of gut microbiota-associated tryptophan metabolism has been
observed in patients with multiple sclerosis. However, defining direct mechanistic links …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Intestinal inflammatory disorders are associated with neurophysiological and behavioral
symptoms. Conversely, many disorders of the central nervous system (CNS) are …

There is increasing knowledge regarding the role of the microbiome in modulating brain and
behaviour. Indeed, the actions of microbial metabolites are key for appropriate gut-brain …

The identification of intestinal dysbiosis in patients with neurological and psychiatric
disorders has highlighted the importance of gut–brain communication, and yet the question …

The gut is connected to the CNS by immunological mediators, lymphocytes,
neurotransmitters, microbes and microbial metabolites. A mounting body of evidence …

Multiple sclerosis (MS) is an inflammatory demyelinating disorder of the CNS. Bile acids are
cholesterol metabolites that can signal through receptors on cells throughout the body …

Objective To examine the gut microbiota in individuals with and without pediatric‐onset
multiple sclerosis (MS). Methods We compared stool‐derived microbiota of Canadian …