Rhodococcus as Biofactories for Microbial Oil Production

HM Alvarez, MA Hernández, MP Lanfranconi, RA Silva… - Molecules, 2021 - mdpi.com
Bacteria belonging to the Rhodococcus genus are frequent components of microbial
communities in diverse natural environments. Some rhodococcal species exhibit the …

SARS-CoV-2 proteome microarray for global profiling of COVID-19 specific IgG and IgM responses

H Jiang, Y Li, H Zhang, W Wang, X Yang, H Qi… - Nature …, 2020 - nature.com
We still know very little about how the human immune system responds to SARS-CoV-2.
Here we construct a SARS-CoV-2 proteome microarray containing 18 out of the 28 predicted …

Mucor circinelloides: a model organism for oleaginous fungi and its potential applications in bioactive lipid production

ABA Fazili, AM Shah, X Zan, T Naz, S Nosheen… - Microbial cell …, 2022 - Springer
Microbial oils have gained massive attention because of their significant role in industrial
applications. Currently plants and animals are the chief sources of medically and …

Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

J Wang, X Yu, K Wang, L Lin, HH Liu… - Bioresource …, 2023 - Elsevier
Omega-6 polyunsaturated fatty acids (ω6-PUFAs), such as γ-linolenic acid (GLA), dihomo-γ-
linolenic acid (DGLA) and arachidonic acid (ARA), are indispensable nutrients for human …

Global profiling of SARS-CoV-2 specific IgG/IgM responses of convalescents using a proteome microarray

H Jiang, Y Li, H Zhang, W Wang, D Men, X Yang, H Qi… - MedRxiv, 2020 - medrxiv.org
COVID-19 is caused by SARS-CoV-2, and has become a global pandemic. There is no
highly effective medicine or vaccine, most of the patients were recovered by their own …

Lipid production by robust Aspergillus oryzae BCC7051 and a mathematical model describing its growth and lipid phenotypic traits

S Wannawilai, T Palasak, W Chamkhuy… - Journal of Applied …, 2024 - academic.oup.com
Aims To identify the promising oleaginous Aspergillus oryzae strain and leverage its lipid
and biomass production through a mathematical model. Methods and results Comparative …

Construction of DGLA producing cell factory by genetic modification of Mucor circinelloides

MAK Khan, J Yang, SA Hussain, H Zhang, L Liang… - Microbial Cell …, 2019 - Springer
Background Dihomo-gamma linolenic acid (DGLA, 20: 3, n-6) is the elongated product of
Gamma linolenic acid (GLA, 18: 3, n-6) catalyzed by the enzyme delta-6 elongase (D6E) or …

[HTML][HTML] Novel pentose-regulated promoter of Aspergillus oryzae with application in controlling heterologous gene expression

S Jeennor, J Anantayanon, C Chutrakul… - Biotechnology …, 2022 - Elsevier
The potent promoter and its transcriptional control make a significant contribution to strain
optimization. Using transcriptome-based approach, a novel pentose-regulated promoter of …

Δ6 fatty acid desaturases in polyunsaturated fatty acid biosynthesis: insights into the evolution, function with substrate specificities and biotechnological use

J Cui, H Chen, X Tang, J Zhao, H Zhang… - Applied Microbiology …, 2020 - Springer
Δ6 fatty acid desaturases (FADS6) have different substrate specificities that impact the ratio
of omega-6/omega-3 polyunsaturated fatty acids, which are involved in regulating multiple …

Progress in the genetic engineering of cereals to produce essential polyunsaturated fatty acids

J Kraic, D Mihálik, L Klčová, M Gubišová… - Journal of …, 2018 - Elsevier
Essential polyunsaturated fatty acids with more than two double bonds and length of carbon
chain 18–22 must be taken in the diet to prevent diseases and imbalances caused by their …