Catalytic asymmetric organozinc additions to carbonyl compounds

L Pu, HB Yu - Chemical Reviews, 2001 - ACS Publications
Since the initial report of Oguni and Omi on the reaction of diethylzinc with benzaldehyde in
the presence of a catalytic amount of (S)-leucinol with moderate enantioselectivity (49% ee) …

Stereoselective synthesis, synthetic and pharmacological application of monoterpene-based 1, 2, 4-and 1, 3, 4-oxadiazoles

T Gonda, P Bérdi, I Zupkó, F Fülöp… - International Journal of …, 2017 - mdpi.com
Stereoselective synthesis of monoterpene-based 1, 2, 4-and 1, 3, 4-oxadiazole derivatives
was accomplished starting from α, β-unsaturated carboxylic acids, obtained by the oxidation …

Chiral aminoalcohols with a menthane skeleton as catalysts for the enantioselective addition of diethylzinc to benzaldehyde

S Panev, A Linden, V Dimitrov - Tetrahedron: Asymmetry, 2001 - Elsevier
Novel chiral aminoalcohols were synthesized by highly diastereoselective addition of
Me3SiCN and LiCH2CN to (−)-menthone followed by LiAlH4 reduction. The addition of …

[PDF][PDF] ENANTIOSELECTIVE ORGANOZINC-CATALYZED ADDITIONS TO CARBONYL COMPOUNDS–RECENT DEVELOPMENTS

V Dimitrov, M Kamenova-Nacheva - Journal of the University of …, 2009 - researchgate.net
The realization of enantioselective CC-bond forming reactions is of immense importance in
the modern organic synthesis. The global needs of pharmaceutical industry and the fast …

Synthesis and medicinal chemical characterisation of antiproliferative O, N-functionalised isopulegol derivatives

TM Le, IK Njangiru, A Vincze, I Zupkó, GT Balogh… - RSC …, 2024 - pubs.rsc.org
Benzylation of isopulegol furnished O-benzyl-protected isopulegol, which was transformed
into aminodiols via epoxidation followed by ring opening of the corresponding epoxides and …

The chemistry of epoxy alcohols

PCA Pena, SM Roberts - Current Organic Chemistry, 2003 - ingentaconnect.com
Epoxy alcohols are extremely versatile building blocks in organic synthesis, due to their
general availability in both enantiomeric series. The preferred methods for the subsequent …

Stereoselective synthesis of pinane-type tridentate aminodiols and their application in the enantioselective addition of diethylzinc to benzaldehyde

K Csillag, L Németh, TA Martinek, Z Szakonyi… - Tetrahedron …, 2012 - Elsevier
A library of pinane-based aminodiols were prepared from commercially available (1R)-(−)-
myrtenol (−)-1. Compound (−)-1 was transformed into allyl trichloroacetamide (+)-2 via the …

New bis-steroidal axially chiral diols as ligands for the asymmetric addition of diethylzinc to aldehydes

K Kostova, M Genov, I Philipova, V Dimitrov - Tetrahedron: Asymmetry, 2000 - Elsevier
New bis-steroidal axially chiral diols as ligands for the asymmetric addition of diethylzinc to
aldehydes - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Stereoselective Synthesis and Catalytical Application of Perillaldehyde-Based 3-Amino-1, 2-diol Regioisomers

MB Háznagy, A Csámpai, I Ugrai, B Molnár… - International Journal of …, 2024 - mdpi.com
A library of regioisomeric monoterpene-based aminodiols was synthesised and applied as
chiral catalysts in the addition of diethylzinc to benzaldehyde. The synthesis of the first type …

Chiral Modular n‐Butyllithium Aggregates: nBuLi Complexes with Anisyl Fencholates

B Goldfuss, M Steigelmann… - … –A European Journal, 2001 - Wiley Online Library
Chiral, enantiopure aggregates are formed spontaneously by mixing solutions of n‐
butyllithium with anisyl fenchols. X‐ray crystal analyses reveal the structures of these …