Chronic activation of the renin‐angiotensin‐aldosterone system (RAAS) promotes and
perpetuates the syndromes of congestive heart failure, systemic hypertension, and chronic …

Chronic degenerative mitral valve disease as a result of myxomatous degeneration (MMVD)
is the most common acquired cardiovascular disease in the dog representing 75% of all …

This report, issued by the ACVIM Specialty of Cardiology consensus panel, revises
guidelines for the diagnosis and treatment of myxomatous mitral valve disease (MMVD, also …

OBJECTIVES There is a growing understanding of the complexity of interplay between renal
and cardiovascular systems in both health and disease. The medical profession has …

В монографии на основе новейших прикладных и фундаментальных достижений
ветеринарной медицины рассматривается наиболее распространенная патология …

Background The renin‐angiotensin‐aldosterone system (RAAS), when chronically activated,
is harmful and RAAS‐suppressive drugs are beneficial in the treatment of congestive heart …

Aldosterone binds to the mineralocorticoid receptor (NR3C2), a transcription factor of the
nuclear receptor family, present in the kidney and in various other non‐epithelial cells …

Background Furosemide is the only loop diuretic recommended by the ACVIM consensus
guidelines for treatment of congestive heart failure (CHF) in dogs related to degenerative …

Myxomatous mitral valve disease (MMVD) causing mitral regurgitation is the most important
disease of the heart in small animal cardiovascular medicine. Because MMVD is an …

OBJECTIVES: Diuretic therapy reduces preload and relieves congestion secondary to
cardiac dysfunction. Torsemide (torasemide) is a loop diuretic with longer duration of action …