Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Although chronological age correlates with various age‐related diseases and conditions, it
does not adequately reflect an individual's functional capacity, well‐being, or mortality risk …

DNA methylation (DNAm)-based age clocks have been studied extensively as a biomarker
of human ageing and a risk factor for age-related diseases. Despite different tissues having …

Epigenetic changes are known to accrue in normal cells as a result of ageing and
cumulative exposure to cancer risk factors. Increasing evidence points towards age-related …

Senescence of adipose precursor cells (APC) impairs adipogenesis, contributes to the age‐
related subcutaneous adipose tissue (SAT) dysfunction, and increases risk of type 2 …

Aging clocks have provided one of the most important recent breakthroughs in the biology of
aging, and may provide indicators for the effectiveness of interventions in the aging process …

Background With two well‐validated aging measures capturing mortality and morbidity risk,
this study examined whether and to what extent aging mediates the associations of …

Abstract Changes in DNA methylation (DNAm) are linked to aging. Here, we profile highly
conserved CpGs in 339 predominantly female mice belonging to the BXD family for which …

Usage of the phrase “biological age” has picked up considerably since the advent of aging
clocks and it has become commonplace to describe an aging clock's output as biological …

Immunoglobulin G is posttranslationally modified by the addition of complex N-glycans
affecting its function and mediating inflammation at multiple levels. IgG glycome composition …