The integrated brain network that controls respiration

F Krohn, M Novello, RS van der Giessen, CI De Zeeuw… - Elife, 2023 - elifesciences.org
Respiration is a brain function on which our lives essentially depend. Control of respiration
ensures that the frequency and depth of breathing adapt continuously to metabolic needs. In …

Cerebellar modules and their role as operational cerebellar processing units

R Apps, R Hawkes, S Aoki, F Bengtsson, AM Brown… - The Cerebellum, 2018 - Springer
The compartmentalization of the cerebellum into modules is often used to discuss its
function. What, exactly, can be considered a module, how do they operate, can they be …

Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

KJE Matson, DE Russ, C Kathe, I Hua, D Maric… - Nature …, 2022 - nature.com
After spinal cord injury, tissue distal to the lesion contains undamaged cells that could
support or augment recovery. Targeting these cells requires a clearer understanding of their …

Harmol promotes α-synuclein degradation and improves motor impairment in Parkinson's models via regulating autophagy-lysosome pathway

J Xu, YL Ao, C Huang, X Song, G Zhang, W Cui… - npj Parkinson's …, 2022 - nature.com
The abnormal accumulation of α-synuclein (α-syn) is a crucial factor for the onset and
pathogenesis of Parkinson's disease (PD), and the autophagy-lysosome pathway (ALP) …

Global connectivity and function of descending spinal input revealed by 3D microscopy and retrograde transduction

Z Wang, B Maunze, Y Wang, P Tsoulfas… - Journal of …, 2018 - Soc Neuroscience
The brain communicates with the spinal cord through numerous axon tracts that arise from
discrete nuclei, transmit distinct functions, and often collateralize to facilitate the coordination …

Emotional disorders and the cerebellum: neurobiological substrates, neuropsychiatry, and therapeutic implications

JD Schmahmann - Handbook of clinical neurology, 2021 - Elsevier
The notion that the cerebellum is devoted exclusively to motor control has been replaced by
a more sophisticated understanding of its role in neurological function, one that includes …

Clinical heterogeneity of essential tremor: understanding neural substrates of action tremor subtypes

A Fanning, SH Kuo - The Cerebellum, 2024 - Springer
Essential tremor (ET) is a common movement disorder affecting millions of people. Studies
of ET patients and perturbations in animal models have provided a foundation for the neural …

Behavioural and histological changes in cuprizone-fed mice

MK Sen, MSM Almuslehi, JR Coorssen… - Brain, behavior, and …, 2020 - Elsevier
Feeding cuprizone (CPZ) to mice causes demyelination and reactive gliosis in the central
nervous system (CNS), hallmarks of some neurodegenerative diseases like multiple …

The tracts, cytoarchitecture, and neurochemistry of the spinal cord

S Tan, RLM Faull, MA Curtis - The Anatomical Record, 2023 - Wiley Online Library
The human spinal cord can be described using a range of nomenclatures with each
providing insight into its structure and function. Here we have comprehensively reviewed the …

Molecular logic of spinocerebellar tract neuron diversity and connectivity

M Baek, V Menon, TM Jessell, AW Hantman, JS Dasen - Cell Reports, 2019 - cell.com
Coordinated motor behaviors depend on feedback communication between peripheral
sensory systems and central circuits in the brain and spinal cord. Relay of muscle-and …