A review on multifaceted biomedical applications of heparin nanocomposites: Progress and prospects

MK Meher, G Naidu, A Mishra, KM Poluri - International Journal of …, 2024 - Elsevier
Advances in polymer-based nanocomposites have revolutionized biomedical applications
over the last two decades. Heparin (HP), being a highly bioactive polymer of biological …

[HTML][HTML] The role of von Willebrand factor in breast cancer metastasis

CY Goh, S Patmore, A Smolenski, J Howard… - Translational …, 2021 - Elsevier
Breast cancer is the most common female cancer globally, with approximately 12% of
patients eventually developing metastatic disease. Critically, limited effective treatment …

Evolution of heparin anticoagulants to ultra-low-molecular-weight heparins: a review of pharmacologic and clinical differences and applications in patients with cancer

JM Walenga, GH Lyman - Critical reviews in oncology/hematology, 2013 - Elsevier
The burden of venous thromboembolism (VTE) is high in patients with cancer, particularly
those with metastatic disease and those receiving chemotherapy. The use of heparin and …

Non-anticoagulant effects of low molecular weight heparins in inflammatory disorders: A review

Y Yan, Y Ji, N Su, X Mei, Y Wang, S Du, W Zhu… - Carbohydrate …, 2017 - Elsevier
Low molecular weight heparins (LMWHs) are produced by chemical or enzymatic
depolymerization of unfractionated heparin (UFH). Besides their well-known anticoagulant …

Bemiparin, an effective and safe low molecular weight heparin: a review

MM Ciccone, F Cortese, F Corbo, NE Corrales… - Vascular …, 2014 - Elsevier
Bemiparin is a low molecular weight heparin (LMWH) indicated for the acute treatment of
deep vein thrombosis with or without pulmonary embolism, for the prophylaxis of venous …

Adjuvant therapy with bemiparin in patients with limited-stage small cell lung cancer: results from the ABEL study

R Lecumberri, GL Vivanco, A Font, EG Billalabeitia… - Thrombosis research, 2013 - Elsevier
Introduction The haemostatic system plays an important role in the process of cancer
development and spread. Anticoagulants, mainly low molecular weight heparins, could …

Development of low molecular weight heparin by H2O2/ascorbic acid with ultrasonic power and its anti-metastasis property

X Shen, Z Liu, J Li, D Wu, M Zhu, L Yan, G Mao… - International journal of …, 2019 - Elsevier
Low molecular weight heparins (LMWHs) are currently used as an anticoagulant agent
since unfractionated heparin (UFH) can cause serious adverse drug reactions. LMWHs are …

Inhibitory potential of low molecular weight Heparin in cell adhesion; emphasis on tumor metastasis

U Ejaz, F Akhtar, J Xue, X Wan, T Zhang… - European Journal of …, 2021 - Elsevier
Low molecular weight heparin is a Heparin derivative, produced from commercial-grade
Heparin through Chemical or enzymatic depolymerization. LMWH has remained a favored …

Anticoagulants versus cancer

C Tieken, HH Versteeg - Thrombosis research, 2016 - Elsevier
Venous thromboembolism (VTE) and cancer are strongly associated, and present a major
challenge in cancer patient treatment. Cancer patients have a higher risk of developing VTE …

Pharmacological effects and clinical applications of ultra low molecular weight heparins

Z Liu, S Ji, J Sheng, F Wang - Drug discoveries & therapeutics, 2014 - jstage.jst.go.jp
Heparin, one of the common anticoagulants, is clinically used to prevent and treat venous
thromboembolism (VTE). Though it has been the drug of choice for many advanced medical …