The overlapping metabolic reprogramming of cancer and immune cells is a putative
determinant of the antitumor immune response in cancer. Increased evidence suggests that …

Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis
and recurrence rate, and adipocytes are the largest components in breast tissue. The …

Aggressive and metastatic cancers show enhanced metabolic plasticity, but the precise
underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA …

Simple Summary Cancer is one of the most debated problems all over the world. Cancer
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …

Abstract PFKFB3 (6-phosphofructo-2-kinase) is the rate-limiting enzyme of glycolysis and is
overexpressed in several human cancers that are associated with poor prognosis. High …

Cell identity is largely determined by its transcriptional profile. In tumour, deregulation of
transcription factor expression and/or activity enables cancer cell to acquire a stem-like state …

An effective systemic mechanism regulates tumor development and progression; thus, a
rational design in a one‐stone‐two‐birds strategy is meant for cancer treatment. Herein, a …

The tumor suppressor p53 maintains an equilibrium between self-renewal and
differentiation to sustain a limited repertoire of stem cells for proper development and …

Cancer remains the leading cause of death and rapidly evolving disease worldwide. The
understanding of disease pathophysiology has improved through advanced research …

In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We
first provide an overview of glutamine metabolism, and then summarize relevant studies …