On the rise and fall of the apnea− hypopnea index: A historical review and critical appraisal

DA Pevernagie, B Gnidovec‐Strazisar… - Journal of sleep …, 2020 - Wiley Online Library
Summary The publication of “The Sleep Apnea Syndromes” by Guilleminault et al. in the
1970s hallmarked the discovery of a new disease entity involving serious health …

Phenotypic subtypes of OSA: a challenge and opportunity for precision medicine

A Zinchuk, HK Yaggi - Chest, 2020 - Elsevier
Current strategies for the management of OSA reflect a one-size-fits-all approach. Diagnosis
and severity of OSA are based on the apnea-hypopnea index and treatment initiated with …

Challenges and perspectives in obstructive sleep apnoea: report by an ad hoc working group of the Sleep Disordered Breathing Group of the European Respiratory …

W Randerath, CL Bassetti… - European respiratory …, 2018 - Eur Respiratory Soc
Obstructive sleep apnoea (OSA) is a major challenge for physicians and healthcare systems
throughout the world. The high prevalence and the impact on daily life of OSA oblige …

Sleep apnea physiological burdens and cardiovascular morbidity and mortality

G Labarca, D Vena, WH Hu, N Esmaeili… - American Journal of …, 2023 - atsjournals.org
Rationale: Obstructive sleep apnea is characterized by frequent reductions in ventilation,
leading to oxygen desaturations and/or arousals. Objectives: In this study, association of …

Review and perspective on sleep-disordered breathing research and translation to clinics

H Korkalainen, S Kainulainen, AS Islind… - Sleep Medicine …, 2023 - Elsevier
Sleep-disordered breathing, ranging from habitual snoring to severe obstructive sleep
apnea, is a prevalent public health issue. Despite rising interest in sleep and awareness of …

Reinventing polysomnography in the age of precision medicine

DC Lim, DR Mazzotti, K Sutherland, JW Mindel… - Sleep medicine …, 2020 - Elsevier
For almost 50 years, sleep laboratories around the world have been collecting massive
amounts of polysomnographic (PSG) physiological data to diagnose sleep disorders, the …

[HTML][HTML] New technology to assess sleep apnea: wearables, smartphones, and accessories

T Penzel, C Schöbel, I Fietze - F1000Research, 2018 - ncbi.nlm.nih.gov
Sleep medicine has been an expanding discipline during the last few decades. The
prevalence of sleep disorders is increasing, and sleep centers are expanding in hospitals …

A review of approaches for analysing obstructive sleep apnoea‐related patterns in pulse oximetry data

PI Terrill - Respirology, 2020 - Wiley Online Library
Overnight pulse oximetry allows the relatively non‐invasive estimation of peripheral blood
haemoglobin oxygen saturations (SpO2), and forms part of the typical polysomnogram …

Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea

S Hietakoste, H Korkalainen, S Kainulainen… - Scientific reports, 2020 - nature.com
Low long-term heart rate variability (HRV), often observed in obstructive sleep apnea (OSA)
patients, is a known risk factor for cardiovascular diseases. However, it is unclear how the …

Phenotyping the pathophysiology of obstructive sleep apnea using polygraphy/polysomnography: a review of the literature

M Bosi, A De Vito, B Kotecha, L Viglietta… - Sleep and …, 2018 - Springer
Continuous positive airway pressure (CPAP) is the first-line treatment for the majority of
patients affected by obstructive sleep apnea syndrome (OSA). However, long-term …