Nonalcoholic fatty liver disease

EM Brunt, VWS Wong, V Nobili, CP Day… - Nature reviews Disease …, 2015 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a disorder characterized by excess accumulation
of fat in hepatocytes (nonalcoholic fatty liver (NAFL)); in up to 40% of individuals, there are …

[HTML][HTML] Nonalcoholic fatty liver disease: a precursor of the metabolic syndrome

A Lonardo, S Ballestri, G Marchesini, P Angulo… - Digestive and Liver …, 2015 - Elsevier
The conventional paradigm of nonalcoholic fatty liver disease representing the “hepatic
manifestation of the metabolic syndrome” is outdated. We identified and summarized …

Altered fecal microbiota correlates with liver biochemistry in nonobese patients with non-alcoholic fatty liver disease

B Wang, X Jiang, M Cao, J Ge, Q Bao, L Tang… - Scientific reports, 2016 - nature.com
Increasing evidence suggests a role of intestinal dysbiosis in obesity and non-alcoholic fatty
liver disease (NAFLD). But it remains unknown in nonobese NAFLD. This prospective, cross …

Human fatty liver disease: old questions and new insights

JC Cohen, JD Horton, HH Hobbs - Science, 2011 - science.org
Nonalcoholic fatty liver disease (NAFLD) is a burgeoning health problem that affects one-
third of adults and an increasing number of children in developed countries. The disease …

[HTML][HTML] Pathogenesis and prevention of hepatic steatosis

F Nassir, RS Rector, GM Hammoud… - Gastroenterology & …, 2015 - ncbi.nlm.nih.gov
Hepatic steatosis is defined as intrahepatic fat of at least 5% of liver weight. Simple
accumulation of triacylglycerols in the liver could be hepatoprotective; however, prolonged …

Exercise and non-alcoholic fatty liver disease: a systematic review and meta-analysis

SE Keating, DA Hackett, J George, NA Johnson - Journal of hepatology, 2012 - Elsevier
BACKGROUND & AIMS: Exercise is an integral component of lifestyle intervention aimed at
weight loss, but an independent benefit of exercise in NAFLD has also been suggested …

[HTML][HTML] Risk of cardiovascular, cardiac and arrhythmic complications in patients with non-alcoholic fatty liver disease

S Ballestri, A Lonardo, S Bonapace… - World journal of …, 2014 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) has emerged as a public health problem of
epidemic proportions worldwide. Accumulating clinical and epidemiological evidence …

Epigenetic modification of liver mitochondrial DNA is associated with histological severity of nonalcoholic fatty liver disease

CJ Pirola, TF Gianotti, AL Burgueño, M Rey-Funes… - Gut, 2013 - gut.bmj.com
Objective & design Nonalcoholic fatty liver disease (NAFLD) is a clinical condition that refers
to progressive histological changes ranging from simple steatosis (SS) to nonalcoholic …

Non-alcoholic fatty liver disease

BW Smith, LA Adams - Critical reviews in clinical laboratory …, 2011 - Taylor & Francis
Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic steatosis not
due to excess alcohol consumption. The prevalence of NAFLD is up to 30% in developed …

Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment

BW Smith, LA Adams - Nature Reviews Endocrinology, 2011 - nature.com
Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) frequently
coexist as they share the pathogenic abnormalities of excess adiposity and insulin …