The relationship between metabolism and cell cycle progression is complex and
bidirectional. Cells must rewire metabolism to meet changing biosynthetic demands across …

Glucans are the most abundant class of macromolecule polymers in fungi, which are
commonly found in Ascomycota and Basidiomycota. Fungal glucans are not only essential …

The recently observed circadian oscillations of the intestinal microbiota underscore the
profound nature of the human–microbiome relationship and its importance for health …

A fundamental problem in biology is how cells obtain the reproducible, coherent phenotypes
needed for natural selection to act or, put differently, how cells manage to limit their …

The field of developmental metabolism is experiencing a technological revolution that is
opening entirely new fields of inquiry. Advances in metabolomics, small-molecule sensors …

Background In addition to functioning as a precise monitoring mechanism in cell cycle, the
anaphase-promoting complex/cyclosome (APC/C) is reported to be involved in regulating …

How cells coordinate their metabolism with division determines the rate of cell proliferation.
Dynamic patterns of metabolite synthesis during the cell cycle are unexplored. We report the …

Proteins are the principal macromolecular constituent of proliferating cells, and protein
synthesis is viewed as a primary metric of cell growth. While there are celebrated examples …

Profiling the repertoire of proteins associated with a given mRNA during the cell cycle is
unstudied. Furthermore, it is easier to ask and answer what mRNAs a specific protein might …

The interplay between cellular mechanics and biochemical processes in the cell cycle is not
well understood. We propose a quantitative model of cell budding in Saccharomyces …