[HTML][HTML] Metabolite interactions between host and microbiota during health and disease: Which feeds the other?

Y Zhang, R Chen, DD Zhang, S Qi, Y Liu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Metabolites produced by the host and microbiota play a crucial role in how human bodies
develop and remain healthy. Most of these metabolites are produced by microbiota and …

A century of studying plant secondary metabolism—from “what?” to “where, how, and why?”

RA Dixon, AJ Dickinson - Plant Physiology, 2024 - academic.oup.com
Over the past century, early advances in understanding the identity of the chemicals that
collectively form a living plant have led scientists to deeper investigations exploring where …

Engineering yeast for the de novo synthesis of jasmonates

H Tang, S Lin, J Deng, JD Keasling, X Luo - Nature Synthesis, 2024 - nature.com
Jasmonates are a class of plant hormones with many agricultural applications and potential
medicinal properties. However, the low content of jasmonates in plants and environmental …

[HTML][HTML] Towards understanding of fungal biocontrol mechanisms of different yeasts antagonistic to Botrytis cinerea through exometabolomic analysis

A Fernandez-San Millan, J Gamir, L Larraya, I Farran… - Biological Control, 2022 - Elsevier
There is increased interest in research on yeasts as potential phytopathogen biocontrol
agents due to increasing restrictions in the use of chemical pesticides. Yeast strains from a …

[HTML][HTML] Identification of new antifungal metabolites produced by the yeast Metschnikowia pulcherrima involved in the biocontrol of postharvest plant pathogenic fungi

A Fernandez-San Millan, J Gamir, I Farran… - Postharvest Biology and …, 2022 - Elsevier
Several strains of the yeast Metschnikowia pulcherrima exhibit strong antagonistic activity
against postharvest pathogens and may have broad biotechnological potential as biocontrol …

Metabolomics and Microbial Metabolism: Toward a Systematic Understanding

D Holbrook-Smith, J Trouillon… - Annual Review of …, 2023 - annualreviews.org
Over the past decades, our understanding of microbial metabolism has increased
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …

Tyr‐Asp inhibition of glyceraldehyde 3‐phosphate dehydrogenase affects plant redox metabolism

JC Moreno, BE Rojas, R Vicente, M Gorka… - The EMBO …, 2021 - embopress.org
How organisms integrate metabolism with the external environment is a central question in
biology. Here, we describe a novel regulatory small molecule, a proteogenic dipeptide Tyr …

Network medicine: an approach to complex kidney disease phenotypes

AK Pandey, J Loscalzo - Nature Reviews Nephrology, 2023 - nature.com
Scientific reductionism has been the basis of disease classification and understanding for
more than a century. However, the reductionist approach of characterizing diseases from a …

The knowns and unknowns in protein–metabolite interactions

I Kurbatov, G Dolgalev, V Arzumanian… - International Journal of …, 2023 - mdpi.com
Increasing attention has been focused on the study of protein–metabolite interactions (PMI),
which play a key role in regulating protein functions and directing an orchestra of cellular …

An overview of technologies for MS-based proteomics-centric multi-omics

AT Rajczewski, PD Jagtap, TJ Griffin - Expert review of proteomics, 2022 - Taylor & Francis
Introduction Mass spectrometry-based proteomics reveals dynamic molecular signatures
underlying phenotypes reflecting normal and perturbed conditions in living systems …