CR Bezzina, N Lahrouchi, SG Priori - Circulation research, 2015 - Am Heart Assoc
Sudden cardiac death occurs in a broad spectrum of cardiac pathologies and is an important cause of mortality in the general population. Genetic studies conducted during the past 20 …
CR Bezzina, J Barc, Y Mizusawa, CA Remme… - Nature …, 2013 - nature.com
Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A mutations in around 20% of cases,,. Through a genome-wide association study of 312 …
JD Kapplinger, DJ Tester, M Alders, B Benito, M Berthet… - Heart rhythm, 2010 - Elsevier
BACKGROUND: Brugada syndrome (BrS) is a common heritable channelopathy. Mutations in the SCN5A-encoded sodium channel (BrS1) culminate in the most common genotype …
SG Priori, E Aliot, C Blomstrom-Lundqvist… - European heart …, 2001 - academic.oup.com
The members of the Task Force on Sudden Death dedicate this paper to the memory of our former friend and colleague, Professor Ronald WF Campbell. Ronnie spent his life working …
AAM Wilde, C Antzelevitch, M Borggrefe, J Brugada… - Circulation, 2002 - Am Heart Assoc
in a superior intercostal space in individuals with high clinical suspicion (aborted sudden cardiac death victims, family members of patients with Brugada syndrome) may also …
Background—Treatment of patients with Brugada syndrome is complicated by the incomplete information on the natural history of the disease related to the small number of …
Objectives: Our objective in this study was to evaluate Tpeak-Tend interval (Tp-e) and other electrocardiographic parameters as risk factors for recurrence of life-threatening cardiac …
J Brugada, R Brugada, C Antzelevitch, J Towbin… - Circulation, 2002 - Am Heart Assoc
Background—The electrocardiographic pattern of right bundle-branch block with ST- segment elevation in leads V1 to V3 is increasingly recognized among patients who have …
H Watanabe, TT Koopmann… - The Journal of …, 2008 - Am Soc Clin Investig
Brugada syndrome is a genetic disease associated with sudden cardiac death that is characterized by ventricular fibrillation and right precordial ST segment elevation on ECG …