Acute kidney injury in patients with cirrhosis

MK Nadim, G Garcia-Tsao - New England Journal of Medicine, 2023 - Mass Medical Soc
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AGA clinical practice update on the use of vasoactive drugs and intravenous albumin in cirrhosis: expert review

G Garcia-Tsao, JG Abraldes, NE Rich, VWS Wong - Gastroenterology, 2024 - Elsevier
Description Cirrhosis is a major cause of morbidity and mortality in the United States and
worldwide. It consists of compensated, decompensated, and further decompensated stages; …

Evaluation of terlipressin-related patient outcomes in hepatorenal syndrome-acute kidney injury using point-of-care echocardiography

M Premkumar, K Kajal, KR Reddy, M Izzy… - Hepatology, 2024 - journals.lww.com
Results: One hundred and forty patients were enrolled (84% men, 59% alcohol-associated
disease, mean MELD-Na 25±SD 5.6). A median daily dose of infused terlipressin was 4.3 …

[HTML][HTML] Acute kidney injury in patients with Cirrhosis: Acute Disease Quality Initiative (ADQI) and international Club of ascites (ICA) joint multidisciplinary consensus …

MK Nadim, JA Kellum, L Forni, C Francoz, SK Asrani… - Journal of …, 2024 - Elsevier
Patients with cirrhosis are prone to develop acute kidney injury (AKI), a complication
associated with a markedly increased in-hospital morbidity and mortality, along with a risk of …

Role of terlipressin in patients with hepatorenal syndrome-acute kidney injury admitted to the ICU: a substudy of the CONFIRM trial

CJ Karvellas, R Subramanian, JC Olson… - Critical Care …, 2023 - journals.lww.com
DESIGN: Patients were randomly assigned in a 2: 1 ratio to receive terlipressin or placebo
for up to 14 days. SETTING: A retrospective analysis of data from the phase III CONFIRM …

Update on Hepatorenal Syndrome: From Pathophysiology to Treatment

S Khemichian, MK Nadim… - Annual Review of …, 2025 - annualreviews.org
Hepatorenal syndrome–acute kidney injury (HRS-AKI) occurs in the setting of advanced
chronic liver disease, portal hypertension, and ascites. HRS-AKI is found in∼ 20% of …

Cost-effectiveness of terlipressin for hepatorenal syndrome: The United States hospital perspective

JA Carter, X Huang, K Jamil, S Corman… - Journal of Medical …, 2023 - Taylor & Francis
Background Hepatorenal syndrome (HRS) is characterized by severely reduced renal
perfusion that precipitates rapid morbidity and mortality. Terlipressin is the only US Food and …

[HTML][HTML] A Comprehensive Systematic Review of the Latest Management Strategies for Hepatorenal Syndrome: A Complicated Syndrome to Tackle

P Roy, N Minhaz, P Shah-Riar, SY Simona, T Tasha… - Cureus, 2023 - ncbi.nlm.nih.gov
Hepatorenal syndrome (HRS), defined by the extreme manifestation of renal impairment in
patients with cirrhosis, is characterized by reduced renal blood flow and glomerular filtration …

How do network meta-analyses address intransitivity when assessing certainty of evidence: a systematic survey

Y Wang, R Xia, TP Pericic, GE Bekkering, L Hou… - BMJ open, 2023 - bmjopen.bmj.com
Objectives To describe how systematic reviews with network meta-analyses (NMAs) that
used the Grading of Recommendations Assessment, Development, and Evaluation …

Terlipressin versus placebo or noradrenalin in the treatment of hepatorenal syndrome: a systematic review and meta-analysis

YM Wan, SQ Huang, HM Wu, YH Li, HJ Yin… - Frontiers in …, 2024 - frontiersin.org
Background Hepatorenal syndrome (HRS) bears a very poor prognosis with unmet need for
safe and effective therapies. This systematic review and meta-analysis aimed to re-assess …