Digital database of absorption spectra of diverse flavonoids enables structural comparisons and quantitative evaluations

M Taniguchi, CA LaRocca, JD Bernat… - Journal of Natural …, 2023 - ACS Publications
Flavonoids play diverse roles in plants, comprise a non-negligible fraction of net primary
photosynthetic production, and impart beneficial effects in human health from a plant-based …

Structural alterations and inhibition of lysozyme activity upon binding interaction with rotenone: Insights from spectroscopic investigations and molecular dynamics …

S Asgharzadeh, B Shareghi, S Farhadian - International Journal of …, 2024 - Elsevier
The pervasive employment of pesticides such as rotenone on a global scale represents a
substantial hazard to human health through direct exposure. Therefore, exploring the …

Elucidation of molecular interaction of bioactive flavonoid luteolin with human serum albumin and its glycated analogue using multi-spectroscopic and computational …

S Sarmah, S Pahari, VK Belwal, M Jana… - Journal of Molecular …, 2020 - Elsevier
Human serum albumin (HSA), an abundant protein in human plasma, which is associated
with the transportation of numerous drugs, fatty acids to their targets and regulates the blood …

Protective actions of bioactive flavonoids chrysin and luteolin on the glyoxal induced formation of advanced glycation end products and aggregation of human serum …

S Sarmah, S Das, AS Roy - International Journal of Biological …, 2020 - Elsevier
The post-translational modification of proteins by nonenzymatic glycation (NEG) and the
accumulation of AGEs are the two underlying factors associated with the long-term …

A comprehensive in vitro exploration into the interaction mechanism of coumarin derivatives with bovine hemoglobin: Spectroscopic and computational methods

S Lyndem, U Hazarika, P Athul, A Bhatta… - … of Photochemistry and …, 2023 - Elsevier
Biological functioning takes place through the interaction of biomacromolecules with each
other or with other small molecules. The molecular recognition of a carrier protein, bovine …

Multispectroscopic and Theoretical Investigation on the Binding Interaction of a Neurodegenerative Drug, Lobeline with Human Serum Albumin: Perturbation in …

V Rupreo, R Tissopi, K Baruah, AS Roy… - Molecular …, 2024 - ACS Publications
Lobeline (LOB), a naturally occurring alkaloid, has a broad spectrum of pharmacological
activities and therapeutic potential, including applications in central nervous system …

Complexation of turmeric and curcumin mediated silver nanoparticles with human serum albumin: Further investigation into the protein-corona formation, anti-bacterial …

K Baruah, I Konthoujam, S Lyndem, K Aguan… - Spectrochimica Acta Part …, 2023 - Elsevier
Biosynthesized noble metal nanoparticles have been of recent interest due to their broad
implications in the future biomedicinal field. We have synthesized silver nanoparticle using …

Mitigation of ribose and glyoxal induced glycation, AGEs formation and aggregation of human serum albumin by citrus fruit phytochemicals naringin and naringenin …

S Sarmah, A Goswami, VK Belwal, AS Roy - Food Research International, 2022 - Elsevier
Human serum albumin (HSA) being the most prevalent protein in the plasma is extremely
vulnerable to glycation. Two flavonoids naringin and naringenin were tested for their effects …

Deciphering the intriguing molecular recognition of a novel indene-phloroglucinol tethered compound with human serum albumin using multi-spectroscopy and …

G Kalita, S Sarmah, V Prakash, PN Chatterjee… - Journal of Molecular …, 2024 - Elsevier
A new indene-phloroglucinol tethered compound IPC1 was synthesized in our laboratory in
three steps. The interaction of the final compound IPC1 with human serum albumin (HSA) …

Protein‐binding characteristics of yohimbine, a natural indole alkaloid‐based drug for erectile dysfunction

V Rupreo, S Luikham, J Bhattacharyya - Luminescence, 2022 - Wiley Online Library
Even today, talking about sexual dysfunction largely remains a taboo. Therefore less studies
have been recorded and fewer remedies given. Erectile dysfunction (ED) is one of the most …