Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …

Aptamers are single stranded oligonucleotides that bind a wide range of biological targets.
Although aptamers can be isolated from pools of random sequence oligonucleotides using …

G‐quadruplexes are secondary structures formed in G‐rich sequences in DNA and RNA.
Considerable research over the past three decades has led to in‐depth insight into these …

G-quadruplexes are noncanonical nucleic acid structures formed from stacked guanine
tetrads. They are frequently used as building blocks and functional elements in fields such …

Physiological changes in GTP levels in live cells have never been considered a regulatory
step of RAC1 activation because intracellular GTP concentration (determined by …

The G-quadruplexes form highly stable nucleic acid structures, which are implicated in
various biological processes in both DNA and RNA. Although DNA G-quadruplexes have …

In vitro selection queries large combinatorial libraries for sequence-defined polymers with
target binding and reaction catalysis activity. While the total sequence space of these …

Aberrant expression of PDGFR-β is associated with a number of diseases. The G-
quadruplexes (G4s) formed in PDGFR-β gene promoter are transcriptional modulators and …

It is well-accepted that gene expression is heavily influenced by RNA structure. For instance,
stem-loops and G-quadruplexes (rG4s) are dynamic motifs in mRNAs that influence gene …

G-quadruplexes can multimerize under certain conditions, but the sequence requirements of
such structures are not well understood. In this study, we investigated the ability of all …