Fatty acid metabolism in the progression and resolution of CNS disorders

JFJ Bogie, M Haidar, G Kooij, JJA Hendriks - Advanced drug delivery …, 2020 - Elsevier
Recent advances in lipidomics and metabolomics have unveiled the complexity of fatty acid
metabolism and the fatty acid lipidome in health and disease. A growing body of evidence …

The divergent roles of dietary saturated and monounsaturated fatty acids on nerve function in murine models of obesity

AE Rumora, G LoGrasso, JM Hayes… - Journal of …, 2019 - Soc Neuroscience
Neuropathy is the most common complication of prediabetes and diabetes and presents as
distal-to-proximal loss of peripheral nerve function in the lower extremities. Neuropathy …

Fatty acids: a safe tool for improving neurodevelopmental alterations in down syndrome?

C Martínez-Cué, R Bartesaghi - Nutrients, 2022 - mdpi.com
The triplication of chromosome 21 causes Down syndrome (DS), a genetic disorder that is
characterized by intellectual disability (ID). The causes of ID start in utero, leading to …

Anacardium Occidentale L. Leaf Extracts Protect Against Glutamate/H2O2-Induced Oxidative Toxicity and Induce Neurite Outgrowth: The Involvement of SIRT1/Nrf2 …

C Duangjan, P Rangsinth, S Zhang, M Wink… - Frontiers in …, 2021 - frontiersin.org
Neurodegenerative diseases are linked to neuronal cell death and neurite outgrowth
impairment that are often caused by oxidative stress. Natural products, which have …

Safflower oil body nanoparticles deliver hFGF10 to hair follicles and reduce microinflammation to accelerate hair regeneration in androgenetic alopecia

J Kong, W Qiang, J Jiang, X Hu, Y Chen, YX Guo… - International Journal of …, 2022 - Elsevier
Androgenetic alopecia (AGA) affects physical and mental health with limited therapeutic
options. Novel materials and delivery methods have considerable potential to improve the …

[HTML][HTML] Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma

D Spencer, D Yu, RA Morshed, G Li, KC Pituch… - Theranostics, 2019 - ncbi.nlm.nih.gov
Glioblastoma (GBM) remains the most lethal and untreatable central nervous system
malignancy. The challenges to devise novel and effective anti-tumor therapies include …

High-fat diet enhances cell proliferation and compromises intestinal permeability in a translational canine intestinal organoid model

I Nagao, YM Ambrosini - BMC Molecular and Cell Biology, 2024 - Springer
Background Emerging evidence underscores the responsiveness of the mammalian
intestine to dietary cues, notably through the involvement of LGR5+ intestinal stem cells in …

Maternal safflower oil consumption improve reflex maturation, memory and reduces hippocampal oxidative stress in the offspring rats treated during pregnancy and …

MA de Souza, MSC Gomes, AE da Silva… - Journal of Affective …, 2022 - Elsevier
Objective Evaluate the influence of maternal consumption of safflower oil on reflex
maturation, memory and offspring hippocampal oxidative stress. Methodology Two groups …

Oleogels based on palmitic acid and safflower oil: novel formulations for ocular drug delivery of voriconazole

B Mohanty, K Pal, D Quereshi, SK Nayak… - European Journal of …, 2020 - Wiley Online Library
The gelation of the vegetable oils using fat crystals has gained significant attention in recent
years. These formulations have been explored for food and pharmaceutical applications …

Spondias mombin Seed Oil Compounds Identification by Raman Spectroscopy and NMR

PY López-Camacho, JC Martínez-Espinosa… - Applied Sciences, 2021 - mdpi.com
Spondias mombin L. has been used in traditional medicine to treat some cases such as
infections and inflammations. Some researchers have reported that its biological …