Extracellular vesicles (EVs) hold great promise as therapeutic modalities due to their
endogenous characteristics, however, further bioengineering refinement is required to …

The progress in human disease treatment can be greatly advanced through the
implementation of nanomedicine. This approach involves targeted and cell-specific therapy …

Changes that accompany older age can alter the pharmacokinetics (PK),
pharmacodynamics (PD), and likelihood of adverse effects (AEs) of a drug. However, older …

The use of data from randomized clinical trials to justify treatment decisions for real‐world
patients is the current state of the art. It relies on the assumption that average treatment …

Introduction Emicizumab is an effective new treatment option for people with hemophilia A
(PwHA). The approved dosing regimens are based on body weight, without the necessity for …

Chronic diseases typically require long-term management through healthy lifestyle practices
and pharmacological intervention. Although efficacious treatments exist, disease control is …

Blood cell‐derived extracellular vesicles (BCEVs) and lipoproteins are the major circulating
nanoparticles in blood that play an important role in intercellular communication. They have …

The purpose of precision dosing is to increase the chances of therapeutic success in
individual patients. This is achieved in practice by adjusting doses to reach precision dosing …

Addressing infectious conditions presents a formidable challenge, primarily due to the
escalating issue of bacterial resistance. This, coupled with limited financial resources and …

Prior to his passing, Dr. Roger Jelliffe, expressed the need for educating future physicians
and clinical pharmacists on the availability of computer-based tools to support dose …