The need for new antibacterial drugs to treat the increasing global prevalence of drug-
resistant bacterial infections has clearly attracted global attention, with a range of existing …

Antimicrobial resistance (AMR) and persistence are associated with an elevated risk of
treatment failure and relapsing infections. They are thus important drivers of increased …

Persisters refer to genetically drug susceptible quiescent (non-growing or slow growing)
bacteria that survive in stress environments such as antibiotic exposure, acidic and …

Most free-living bacteria can attach to surfaces and aggregate to grow into multicellular
communities encased in extracellular polymeric substances called biofilms. Biofilms are …

The development of new and effective antibacterial drugs to treat multi-drug resistant (MDR)
bacteria, especially Gram-negative (G− ve) pathogens, is acknowledged as one of the …

According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …

There is growing global recognition that the continued emergence of multidrug-resistant
bacteria poses a serious threat to human health. Action plans released by the World Health …

Persistent infections involving slow-growing or non-growing bacteria are hard to treat with
antibiotics that target biosynthetic processes in growing cells. Consequently, there is a need …

The continued emergence of multi-drug-resistant bacteria is a major public health concern.
The identification and development of new antibiotics, especially those with new modes of …

A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …