Hepatorenal syndrome: pathophysiology, diagnosis, and management

DA Simonetto, P Gines, PS Kamath - bmj, 2020 - bmj.com
Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

News in pathophysiology, definition and classification of hepatorenal syndrome: a step beyond the International Club of Ascites (ICA) consensus document

P Angeli, G Garcia-Tsao, MK Nadim, CR Parikh - Journal of hepatology, 2019 - Elsevier
Renal dysfunction is a common, life-threatening complication occurring in patients with liver
disease. Hepatorenal syndrome (HRS) has been defined as a purely “functional” type of …

Diagnosis, evaluation, and management of ascites, spontaneous bacterial peritonitis and hepatorenal syndrome: 2021 practice guidance by the American Association …

SW Biggins, P Angeli, G Garcia‐Tsao, P Ginès… - …, 2021 - Wiley Online Library
This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

EASL Clinical Practice Guidelines for the management of patients with decompensated cirrhosis

P Angeli, M Bernardi, C Villanueva, C Francoz… - Journal of …, 2018 - Elsevier
The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

Clinical states of cirrhosis and competing risks

G D'Amico, A Morabito, M D'Amico, L Pasta… - Journal of …, 2018 - Elsevier
The clinical course of cirrhosis is mostly determined by the progressive increase of portal
hypertension, hyperdynamic circulation, bacterial translocation and activation of systemic …

Diagnosis and management of acute kidney injury in patients with cirrhosis: revised consensus recommendations of the International Club of Ascites

P Angeli, P Ginès, F Wong, M Bernardi, TD Boyer… - Gut, 2015 - gut.bmj.com
Acute renal failure (ARF) is a common complication in patients with decompensated
cirrhosis. The traditional diagnostic criteria of renal failure in these patients were proposed in …

Management of the critically ill patient with cirrhosis: a multidisciplinary perspective

MK Nadim, F Durand, JA Kellum, J Levitsky… - Journal of …, 2016 - Elsevier
Methods Prior to the conference, the organizing committee identified topics relevant to the
management of patients with ACLF. A diverse international panel representing multiple …

Nonselective β blockers increase risk for hepatorenal syndrome and death in patients with cirrhosis and spontaneous bacterial peritonitis

M Mandorfer, S Bota, P Schwabl, T Bucsics, N Pfisterer… - Gastroenterology, 2014 - Elsevier
Background & Aims Nonselective β blockers (NSBBs) reduce portal pressure and the risk for
variceal hemorrhage in patients with cirrhosis. However, development of spontaneous …

[PDF][PDF] Neutrophil gelatinase‐associated lipocalin for assessment of acute kidney injury in cirrhosis: a prospective study

P Huelin, E Solà, C Elia, C Solé, A Risso… - …, 2019 - Wiley Online Library
Kidney biomarkers appear to be useful in differential diagnosis between acute tubular
necrosis (ATN) and other types of acute kidney injury (AKI) in cirrhosis, particularly …

[HTML][HTML] Urinary NGAL as a diagnostic and prognostic marker for acute kidney injury in cirrhosis: a prospective study

AS Allegretti, XV Parada, P Endres… - Clinical and …, 2021 - journals.lww.com
METHODS: Urinary NGAL was measured in a prospective cohort of 213 US hospitalized
patients with decompensated cirrhosis (161 with AKI and 52 reference patients without AKI) …